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Diabetes
Diabetes Drugs
48
Pharmacology
Graduate
05/09/2013

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Cards

Term
Dymelor
Definition
Acetohexamide
Sulfonylurea 1st Generation
Term
Diabinese
Definition
Chlorpropamide

Sulfonylurea 1st Generation
contraindicated in renal insufficience
Term
Tolinase
Definition
Tolazamide

Sulfonylurea 1st Generation
Term
Orinase
Definition
Tolbutamide

Sulfonylurea 1st Generation
Term
Glucotrol, Glucotrol XL
Definition
Glipizide

Sulfonylurea 2nd Generation
Given with or without meal
Term
Diabeta, Micronase
Definition
Glyburide

Sulfonylurea 2nd Generation
3 mg Glynase = 5 mg Glyburide
Term
Glynase
Definition
Lyburide micronized

Sulfonylurea 2nd Generation
Term
Amaryl
Definition
Glimepiride

Sulfonylurea 2nd Generation
Begin with 1 mg in renal insufficience
Term
Prandin
Definition
Repaglinide
Meglitinides
Skip dose if meal skipped
Term
Starlix
Definition
Nateglinide

Meglitinide
Efficacy: prandin> starlix
Term
Glucophage
Definition
Metformin

Biguanide
Do not give if femal SrCr >1.4, Male SrCR >1.5
Term
Glucophage XR, Glumetza
Definition
Metformin Extended release

Biguanide
Term
Avandia
Definition
Rosiglitazone

Thiazoladinedions
May be more effective if given BID
Contranidicated in Heart Failure
Term
Actos
Definition
Pioglitazone
Thiazoladinediones
Term
Precose
Definition
Acarbose

Alpha-Glucosidase Inhibitor
Term
Glyset
Definition
Miglitol
Alpha-glucosidase inhibitor
Term
Onglyza
Definition
Saxagliptin

Dipeptidyl Peptidase-4 Inhibitor'
CrCl <50ml/min give 2.5mg qd
Term
Tradjenta
Definition
Linagliptin

Dipeptidyl Peptidase-4 Inhibitor
Not dependent on CrCl
Term
Januvia
Definition
Sitagliptin

Dipeptidyl Peptidase-4 Inhibitor
Dosed based on CrCl
Term
Metaglip
Definition
Combo: Glipizide/Metformin
Term
Glucovance
Definition
Combo: Glyburide/Metformin
Term
Avandaryl
Definition
Combo: Glimepiride/Rosigitazone
Term
Duetact
Definition
Combo: Glimepiride/Pioglitazone
Term
Avandamet
Definition
Combo: Rosiglitazone/ metformin
Term
ACTOplus Met
Definition
Combo: Metformin/Pioglitazone
Term
Janumet
Definition
combo: Metformin/ Januvia (Sitagliptin)
Term
Prandimet
Definition
Combo: Metformin/ Repaglinide (meglitinide)
Term
Kombiglyze XR
Definition
Combo: Metformin/Saxagliptin (DDP4)
Term
Jentadueto
Definition
Combo: Metformin/ Linagliptin (DDp4)
Term
Victoza
Definition
Liraglutide
duration of action ~24 hrs
Incretin Mimetic
Dosed once daily reglardless of meals
Term
Byetta
Definition
Exenatide
duration of action ~8-10 hrs
Incretin Mimetic
dosed 10-15 minutes prior to 2 largests meals of the day
Term
Bydureon
Definition
Exenatide
~2 weeks initail peak, stead state 6-7
Dosed weekly reglardless of meals
Incretin mimetic
Term
Symlin
Definition
Pramlintide
Amylin Mimetic
Term
Apidra
Definition
Glulisine
Rapid Acting Insulin
peak 30-90 Minutes
DA: 1-3 hrs
Term
Novolog
Definition
Aspart
Rapid acting insulin

peak 30-90 Minutes
DA: 3-5hrs
Term
Humalog
Definition
Lispro
Rapid actic insulin

peak 30-90 Minutes
Term
Novolin N
Definition
Human NPH
Peak: 4-12 hrs
Duration of action 10-18 Hours
Term
Humulin N
Definition
Human NPH

Peak: 4-12 hrs
Duration of action 10-18 Hours
Term
Lente Human
Definition
Lente Human
Time to peak: 7-15
Duration: 24 hr
Term
Lantus
Definition
Glargine
Basal Insulin
Peakless
DA 24 hours
Term
Levemir
Definition
Detemir insulin
Peak: 6-8 hrs
Duration of action 19-24 hrs
Term
Novolin 70/30
Definition
NPH + Regular
Term
Humulin 70/30
Definition
NPH + regular
Term
Humulin 50/50
Definition
NPH + Regular
Term
Novolog 70/30
Definition
Insulin aspart protamin + insulin lispro
intermedia + rapid
Term
Novolog 50/50
Definition
Insulin aspart protamin + insulin lispro
intermedia + rapid
Term
Humalog 75/25
Definition
Insulin lispro protamin + insulin lispro
intermedia + rapid
Term
Humalog 50/50
Definition
Insulin lispro protamin + insulin lispro
intermediate + rapid
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