Term
| How do thiazolidinedioines work? |
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Definition
Peroxisome proliferator - activated receptor γ agonists; increases peripheral insulin sensitivity (increases insulin entry into muscle cells; insulin sensitizers |
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Term
| Brand name for pioglitazone |
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Definition
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Term
| Brand name for pioglitazone + metformin? |
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Definition
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Term
| Brand name for Actoplus + glimepiride? |
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Definition
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Term
| Black box warning for thiazolidinediones? |
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Definition
May cause or exacerbate heart failure
possilbe risk of bladder cancer |
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Term
| Describe the cariovascular risk associated with thiazolidinediones? |
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Definition
Use caution in CHF, can cause fluid retention, periphera edema, HF decompensation. |
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Term
| Which inreases risk of MI? |
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Definition
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Term
| Which is better for lipids? |
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Definition
Pioglitazone is better for lipids: rosiglitazone increases LDL (both increase HDL) |
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Term
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Definition
| Statement. Not a question. |
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Term
| How often are thiazolidinediones taken? |
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Definition
| Oce daily, with or without food |
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Term
| Can this drug cause water retention? |
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Definition
YES! This drug can cause water retention and cause your ankles to swell.
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