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Diabetes Thiazolidinedione
Diabetes Thiazolidinedione
11
Pharmacology
Professional
09/13/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
How do thiazolidinedioines work?
Definition

Peroxisome proliferator - activated receptor γ agonists; increases peripheral insulin sensitivity (increases insulin entry into muscle cells; insulin sensitizers

Term
Brand name for pioglitazone
Definition
Actos
Term
Brand name for pioglitazone + metformin?
Definition
Actoplus Met
Term
Brand name for Actoplus + glimepiride?
Definition
Deutact
Term
Black box warning for thiazolidinediones?
Definition

May cause or exacerbate heart failure

 

possilbe risk of bladder cancer

Term
Describe the cariovascular risk associated with thiazolidinediones?
Definition

Use caution in CHF, can cause fluid retention, periphera edema, HF decompensation.

Term
Which inreases risk of MI?
Definition
Rosiglitazone
Term
Which is better for lipids?
Definition

Pioglitazone is better for lipids: rosiglitazone increases LDL (both increase HDL)

Term
[image]
Definition
Statement. Not a question.
Term
How often are thiazolidinediones taken?
Definition
Oce daily, with or without food
Term
Can this drug cause water retention?
Definition

YES! This drug can cause water retention and cause your ankles to swell.

 

 

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