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Devo Block 3 week 2- Cardiovascular Devel
Medical School Human Development Class
43
Medical
Graduate
10/26/2010

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Term
Heart derived from
Definition
mesoderm and neural crest
Term
blood islands contain precursor cells for?
Definition
endothelium and hematopoietic stem cells
Term
Site of blood cell formation as fetus develops
Definition
Yolk sac 1-2 months, Liver 1.5-3 months, Spleen 3-7 months, Bone marrow 4 months-adult {Young Liver Synthesizes Blood}
Term
What comes from the secondary heart field?
Definition
primitive right ventricle, outflow region, and sinus venosus
Term
What comes from the primary heart field?
Definition
Primordial (common) atrium and AV canal
Term
coronary sinus of right atrium derived from?
Definition
left horn of sinus venosus
Term
crista terminalis of right atrium derived from
Definition
rt valve of sinus venosous
Term
valve of Inferior Vena Cava of right atrium derived from
Definition
rt valve of sinus venosus
Term
Valve of coronary sinus of right atrium derived from
Definition
right valve of sinus venosus
Term
smooth area of right atrium derived from
Definition
absorption of sinus venosus, primarily rt horn
Term
Inferior Vena Cava (terminal portion) of right atrium derived from
Definition
rt vitelline vein
Term
Superior Vena Cava of right atrium derived from
Definition
rt common cardinal and proximal anterior cardinal vein
Term
trabeculated part and auricle of right atrium derived from
Definition
primitive rt atrium
Term
Smooth part of left atrium derived from
Definition
absorption of pulmonary vv
Term
Trabeculated part ( in the auricle) of left atrium derived from
Definition
primitive left atrium
Term
What does the cardiac mesenchyme form in th mature heart
Definition
valve leaflets of: mitral, tricuspid, aortic, and pulmonary valves; chordae tendonae; fibrous cardiac skeleton
Term
Adult derivative of proximal outflow region (conus arteriosus)
Definition
ventricle outflow portion of right ventricle and left ventricle (i.e. smooth part of ventricles)
Term
Adult derivative of distal outflow region (truncus arteriosus)
Definition
pulmonary and aortic valves and part of roots of aorta and pulmonary trunk
Term
Adult derivative of aortic sac
Definition
parts of pulmonary and aortic root
Term
Has dorsal and ventral bulbar regions
Definition
Proximal outflow region
Term
has superior and inferior bulbar regions
Definition
distal outflow region
Term
What does the proximal portion of the conotruncal septum become
Definition
cardiac musc
Term
What does the cushion tissue in distal outflow region contribute to?
Definition
formation of aortic and pulmonary valves
Term
What is the arterial spine of the aortic sac derived from?
Definition
neural crest
Term
What does the ventral compartment of the aortic sac become
Definition
root of pulmonary trunk (pulmonary trunk is ventral to aorta)
Term
What does the dorsal compartment of the aortic sac become?
Definition
root of aorta (aorta is dorsal to pulmonary trunk)
Term
Fusion of what structures forms membranous IVS?
Definition
inferior edge of septum dividing proximal outflow region, ventral endocardial cushion of septum intermedium, and superior edge of muscular IVS
Term
Inlet portion of right ventricle derived from?
Definition
primitive right ventricle
Term
what is the outlet portion (infundibulum) of right ventricle derived from?
Definition
proximal outflow region
Term
what is the inlet portion of the left ventricle derived from
Definition
primitive left ventricle
Term
What is the outlet portion (aortic vestibule) of the left ventricle derived from
Definition
proximal outflow region
Term
Ductus venosus
Definition
shunts blood around liver, connects umbilical vein and inferior vena cava
Term
ductus arteriosus
Definition
shunts blood around lungs; connects pulmonary arteries straight to aorta
Term
ductus venosus becomes
Definition
ligamentum venosum on base of liver
Term
ductus arteriosus becomes
Definition
ligamentum arteriosum
Term
umbilical vein becomes
Definition
ligamentum teres of liver
Term
umbilical artery becomes
Definition
medial umbilical ligaments of abdomen
Term
4 CHD's with left to right shunting
Definition
ventricular septal defect, atrial septal defect, endocardial cushion defect, patent ductus arteriosus
Term
4 CHD's with right to left shunting
Definition
tetralogy of Fallot, transposition of the great vessels, hypoplastic left heart, pulmonary stenosis/ atresia
Term
4 CHD's associated with obstructive processes
Definition
coarctation of aorta, aortic stenosis/atresia, pulmonary stenosis, atresia, hypoplastic left heart
Term
When does the heart start beating?
Definition
Day 20-22
Term
What does pharyngeal arch artery #4 become?
Definition
aorta
Term
What does pharyngeal arch artery #6 become?
Definition
ductus arteriosus
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