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| Keratin Layer, Granular Layer, Prickle Cell Layer, Basal Layer, Dermis |
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Definition
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Definition
| Developmental growth patterns of the skin |
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Definition
| Epidermis is mainly composed of |
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Definition
| Type of cells mostly found within the basal layer |
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| Type of cells mostly found within the prickle cell layer |
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Definition
| composed of 2-3 layers of Flattened cells that have lost their nuclei due to continued differentiation |
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Definition
| composed of sheets of overlapping polyhedral Corneocytes |
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Definition
| Elongated, membrane bound organelles where melanin is produced |
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Definition
| Brown/black common form of melanin |
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Definition
| Growing phase of hair growth |
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Definition
| Resting stage of Hair Growth |
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Definition
| Shedding phase of hair growth |
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Definition
Percentage of scalp hairs in
- Anagen
- Catagen
- Telogen |
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Definition
| White part at the base of the nail |
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Definition
| Interface between epidermis and dermis |
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Definition
| Interface between epidermis and dermis |
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Definition
| Interface between epidermis and dermis |
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Definition
| local overgrowth of the blood vessels |
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Definition
| Skin glands found mainly in the palms, soles and axilla. Excretory ducts opens onto skin surface |
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| Aprocine gland (larger than eccrine) |
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Definition
| Gland develops as part of pilosebaceous unit. Found mainly axilla and perineum. Opens into hair follicle. |
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Definition
| Widely distributed gland. Associated with hair follicles and formed from epidermis derived cells |
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Definition
| Result of mixture of increased Sebum (from sebaceous gland), blocked ducts and bacterial activity |
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Definition
| electromagnetic radiation that is mainly absorbed by the keratin layer |
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Definition
| Touch/vibration receptors |
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Definition
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Definition
| Localised flat area of colour change <1cm |
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Definition
| Localised elevated area <5mm |
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| Nodule (larger version of papule) |
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Definition
| Localised elevated area >5mm |
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Definition
| Small fluid filled blister <5mm with/below epidermis |
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Definition
| Large fluid filled Blister >5mm within/below epidermis |
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Definition
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Definition
| Red skin due to vascular dilatation, Blanches on pressure |
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Definition
| Red skin due to extravasatino of blood, will not Blanche on pressure |
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Definition
| Localised flat area of colour change >1cm |
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Definition
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Definition
| compressable dermal swelling |
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Definition
| area of skin loss extending through epidermis into dermis |
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Term
| Innate (non specifice) immunity |
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Definition
| Immunity = No memory, first line in defence of host, immediate maximum response |
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Term
| NK cells, Mast Cells, Dendritic cells, Phagocytes |
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Definition
| Innate immunity cells (name 4) |
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| Adaptive (specific) immunity |
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Definition
| Immunity = Memory, specific, diverse |
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Definition
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Definition
| Specialised protein produced in response to an antigen |
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Definition
| Specialised cells react with antigen on host cell surface, kills infected host cell and activates macrophages |
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Definition
| Produced in bone marrow, mature in thymus. Basis of cell mediated immunity, only recognise PROTEIN Ag |
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Definition
| Basis of humoral immunity, produce antibodies |
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Definition
| Loss of tolerance leads to... |
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Term
- IgE
- Degranulation of mast cells and basophils
- Inflammatory mediators (histamine, prostaglandins)
- Immediate |
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Definition
Hypersensitivity Type 1
- Antibody mediated is
- Ag Binding caused by...
- Releases...
- Type of response |
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Term
- TH1 cells
- delayed
- NO
- Patch testing |
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Definition
Hypersensitivity Type 4
- cell mediated is
- type of response
- response to antu-histamines?
- Investigation |
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Term
| Direct and reduced systemic toxicity |
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Definition
| Topical treatment advantages |
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Term
| Time consuming, messy, difficult to apply correct dosage |
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Definition
| Topical treatment Disadvantages |
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Term
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Definition
| Liquid vehicle, aqueous or alcohol based, Used to treat scalp and other hair bearing areas |
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Term
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Definition
| Semisolid emulsion of oil-in-water. Non greasy, cosmetically acceptable |
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Term
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Definition
| semisolid grease/oil, best for treating dry skin conditions eg eczema. Less accepted by patients |
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Definition
| Transparent semi-solid, non greasy aq emulsion. Best for scalp and hair bearing areas aswell as face |
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Term
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Definition
| Ointment based with high proportion of powder. Stiff constistency, ideal for applying to well defined areas. Used in cooling, drying and soothing bandages. |
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Term
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Definition
| Helps dry skin conditions - reestablishes surface ipid layer. Cosmetically acceptable. 250g-500g weekly. |
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Term
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Definition
| Reduce inflammation by acting as an immune suppressant |
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Definition
| Used in acute exudative eczema, eczema of hands) |
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Definition
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Definition
| Function is collagen synthesis |
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Definition
| Function is histamine release |
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| Acne, Rosacea and Impetigo |
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Definition
| Topical antibiotics can be used to treat |
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Term
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Definition
| Herpes Simplex (cold sore) would be treated with |
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Definition
| Oral Antiviral could be used to treat |
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Definition
| Antiyeast is used to treat |
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Term
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Definition
| Antifungal is used to treat |
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Term
Viral warts, corns, calluses, Keratin plaques.
Salicylic acid. |
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Definition
| Keratinolytics are used to treat..And give an example of a keratinolytic |
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Term
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Definition
| Liquid nitrogen treatment of viral warts |
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Term
| Emollients, Coal tar, vitamin D analogue, topical steroid |
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Definition
| Topical psoriasis treatment |
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Term
| greasy ointments, tar shampoo, steroids in alcohol base |
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Definition
| Treatment for scalp psoriasis |
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Term
Burning
Irritation
Contact allergic dermatitis
Local or systemic toxicity |
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Definition
| Side effects of topical therapies |
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Term
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Definition
| Allergy investigation that detects type 1. |
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Term
Cheap, quick, easy
More senstive than specific IgE Test |
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Definition
| Skin prick test advantages |
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Term
| Nickel hypersensitivity, TB, type 1 diabetes, psoriasis |
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Definition
| Disease associated with Type 4 hypersensitivity |
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Term
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Definition
| Transcription factor activated in response to DNA damage to stop cell division |
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Term
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Definition
| The process by which a normal cell becomes a malignant cancer cell |
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Term
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Definition
| The formation of new blood cells |
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Term
Solar Radiation
genetics
HPV
p53
age
chemicals |
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Definition
| Risk factors for skin cancer |
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Term
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Definition
| Types of non melanoma skin cancer (most common) |
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Term
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Definition
| Malignant Tumour derived from keratinocytes, occurs mainly in sun damaged skin, white people over 55, males immunosuppressed patients |
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Term
| Actinic Keratosis (red spots with scaly surface) |
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Definition
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Definition
| typically on face, locally invasive, no precursors |
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Term
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Definition
| Rare aggressive tumour arising from neuroendocrine cells |
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Term
| cyclobutane pyrimidine dimer (CPD) |
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Definition
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