Term
Key points
Pustules represent collections of ____
Rule out ____ when you see pustules
Pustules can be ____ |
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Definition
neutrophils
infection
sterile |
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Term
| The most common derm disease with negative psychosocial ramifications is ____ |
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Definition
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Term
| ____ are the hallmark of acne |
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Definition
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Term
| Treatment targets multifactorial causes of acne: (3) |
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Definition
androgens,
follicular obstruction and
Propionibacterium acnes |
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Term
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Definition
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Term
| acne Starts with microcomedone- clogged pore> acne bacteria come in and eat that> turn sebum into fatty acids> inflammatory> cystic lesions and acne |
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Definition
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Term
| Definition: disorder affecting pilosebaceous units in the skin. |
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Definition
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Term
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Definition
| non-inflamed comedones to inflammatory papules, pustules, nodules and cysts. |
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Term
| If comdeones are open they are ___ b/c sebum is oxidizing |
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Definition
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Term
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Definition
– common
Starts young, 9-11 years, increases in teenage years, may continue to the 3rd and 4th decade, especially in women |
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Term
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Definition
Steroid acne
Flat wart
Bacterial folliculitis
Rosacea
Adenoma sebaceum
"Steroid acne: can be from oral steroid, topical steroid, all lesions are in same stage (with acne have a bunch of different stages)
Flat warts
Rosacea- usually adults, no comedones but will have pustules
Adenoma sebaceium associated with tubular sclerosis" |
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Term
____ – intraepidermal, intrafollicular collection of neutrophils
____ – occluded pilosebaceous unit with accumulation of keratin, sebum, and inflammatory cells
Extravasation of material through the ruptured wall leads to further dermal inflammation |
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Definition
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Term
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Definition
Androgenic hormones
Follicular Obstruction
Bacteria – Propionibacterium acnes |
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Term
| Acne Topical Treatment: (3) |
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Definition
Benzol Peroxide
Retinoids
-> Tretinoin
-> Adapalene
Antibiotics
-> Erythromycin
-> Clindamycin |
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Term
| Acne Systemic Treatment (3) |
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Definition
Antibiotics (Tetracycline, minocycline)
Isotretinoin (1mg/kg/d x 20 weeks
Hormonal therapy (Yaz, Ortho Tri-Cyclen) |
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Term
Isotretinoin:
For ___ acne
Vitamin ___ analog
Side effects:
All patients get ____!
Dry skin
_____!!
Increased plasma ____
?? Depression |
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Definition
severe
A
chapped lips
Teratogenic
lipids |
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Term
| Acne Patient Education (5) |
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Definition
Diet
Cleanliness
Cosmetics
Picking
Compliance |
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Term
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Definition
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Term
| Rosacea is classified by... |
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Definition
| Papules and pustules with a background of erythema |
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Term
| Eye involvement is common with ____ |
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Definition
rosacea
"Occular rosacea- dry gritty eyes" |
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Term
| Treat rosacea with topical and/or oral ___ |
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Definition
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Term
| rosacea is a Disease of ___(Primarily) |
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Definition
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Term
Definition: a chronic inflammatory disorder affecting the blood vessels and pilosebaceous units of the face
Fairly common
Hx gradual onset
Trigger factors – cause flare |
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Definition
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Term
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Definition
Vascular
Papulopustular
Rhinophyma
Ocular |
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Term
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Definition
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Term
Rosacea Treatment
Topical: (3)
Systemic: (2)
Avoid triggers |
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Definition
sun screen, azaleic acid, metronidazole
tetracycline, isotretinoin |
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Term
Rosacea Course: ____
Complications: (2) |
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Definition
chronic
rhinophyma, telangectasia |
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Term
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Definition
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Term
| Definition: Bacterial infection of hair follicle |
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Definition
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Term
___ is the most common cause of folliculitis
Colinization can occur in the nose, axillae and groin |
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Definition
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Term
| folliculitis is characterized by ... |
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Definition
| Subcorneal pustule at the opening of a hair follicle |
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Term
| Folliculitis Etiology (3) |
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Definition
Staph
Pseudomonas aeruginosa (from hot tubs?)
Fungal infection |
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Term
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Definition
Acne
Pseudofolliculitis barbae (PFB)
Keratosis pilaris (KP) |
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Term
| Folliculitis Diagnosis is via |
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Definition
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Term
| Folliculitis Therapy: (2) |
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Definition
Antiseptic cleansers
-> Betadine
-> Hibiclens
Antibiotics
-> Dicloxacillin |
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Term
| If recurrent folliculitis, patient may be a chronic carrier of ___ or ___ |
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Definition
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Term
| Definition: honey-colored crust |
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Definition
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Term
| ___ is the most common cause of impetigo |
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Definition
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Term
| Treat impetigo with oral or topical ___ |
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Definition
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Term
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Definition
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Term
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Definition
often starts as a single lesion, then spreads
Other family members often affected |
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Term
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Definition
Antibacterial soaps: Lever, Dial, Hibiclens
Change towel/washcloths daily (& don’t share)
Antibiotics – need penicillinase-resistant antibiotics (Cephalexin, erythromycin, dicloxacillin mupirocin ointment |
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Term
| Definition: “Beefy red” erythema with satellite papules and pustules |
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Definition
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Term
_____ is Common in setting of diaper dermatitis
Moisture is a major predisposing factor |
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Definition
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Term
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Definition
| patient complains of itching and burning |
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Term
| A ____ environment is the most important local predisposing factor for candidiasis. Excessive skin folds help to provide a ___ environment. |
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Definition
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Term
| Erosio interdigitalis blastomycetica is what? |
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Definition
| candidiasis in finger webs |
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Term
Candidiasis DDX – depends on location
Groin: (3)
Back: (2) |
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Definition
tinea cruris, intertrigo, irritant dermatitis
miliaria or folliculitis |
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Term
| ___ & ____ are found on KOH examination of candidiasis |
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Definition
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Term
Candidiasis Treatment:
Topical creams (3)
Systemic (2) |
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Definition
Clotrimazole
Miconazole
Ketoconazole
Ketoconazole 200mg daily
Fluconazole 100mg daily |
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Term
Uncommon Causes of Pustules
¨Bacterial sepsis
¡Gonococcal
¡Staphylococcal
¨Fungal infection
¡Dermatophyte (kerion)
¡Deep fungal infection
úCoccidioidomycosis
úBlastomycosis
¨Sterile pustules
¡Pustular psoriasis
¡Subcorneal pustular dermatosis
¡Drugs: iodides, bromides, haloperidol |
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Definition
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Term
| Definition: Dermatophytes can infect hair follicles and may result in pustules |
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Definition
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Term
____: dermatophytic infection usually of the scalp that is indurated boggy inflammatory plaque studded with pustules
Requires systemic ____ therapy |
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Definition
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Term
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Definition
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Term
Rare deep fungal infection presenting with skin manifestations. Due to Inhalation of spores with subsequent dissemination to skin and other organs
Bx and tissue culture confirm diagnosis |
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Definition
| Deep Fungal Infection - Coccidoidomycosis |
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Term
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Definition
| Deep Fungal Infection - Coccidoidomycosis |
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Term
| Coccidoidomycosis is caused by the fungus: |
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Definition
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Term
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Definition
| Subcorneal Pustular Dermatosis |
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Term
| _____ ____ are the hallmark of subcorneal pustular dermatosis |
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Definition
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Term
_____ is Characterized by annular or expanding polycyclic collections of pustules on a red base.
Flexural accentuation is common
Waxing and waning course
Skin bx confirms dx
Dapsone is tx of choice |
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Definition
| Subcorneal Pustular Dermatosis |
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Term
STRING OF PEARLS
ANNULAR STRING OF PUSTULES LIKE A PEARL NECKLACE
is characteristic of _______ |
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Definition
| Subcorneal Pustular Dermatosis |
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