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Derm Midterm
Derm Midterm
40
Other
Professional
01/16/2013

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Term
Raynayd's phenomenon
Definition
another condition commonly associate with rheumatic disease,
characterized by episodic vasospasm resulting in ischemia of the digits,
Term
Diagnosis of Systemic Lupus Erythematosus
Definition
"ANTINUCLEAR," FOUR CRITERIA ARE REQUIRED TO establish A diagnosis
Antinuclear antibody
Neurologic disorder-seizures or psychosis
Thrombocytopenia
Immunologic disorder
Nasopharyngeal or oral ulcers
Urinary abnormalities
Cutaneous discoid rash
Light sensitivity
Effusions
Arthritis of two or more joints
Rash in malar area
Term
Systemic lupus erythematosus
Definition
is an autoimmune disorder associated with a wide array of manifestions, many of whch involve the skin
Term
Livedo reticularis
Definition
is characterized by reticular erythema, which is purplish at times, and most commonly affects the lower extremities
Term
Livedo vasculitis
Definition
called atrophie blance, occurs in some women with persistent deep purple livedo reticularis
Term
Bullous lupus erythematosus
Definition
associate with SLE, separation of subepidermal, and direct immunofluorescence reveals immune deposits at the dermal and epidermal junction.
Term
Bullous lupus erythematosus
Definition
Lupus band test
Term
Dermatomyositis
Definition
is a sign of underlying malignancy, some cases it disappeared with treament of a tumor
Term
Rheumatoid arthritis
Definition
diagnosis include morning stiffness, joint tenderness or pain on motion, joint swelling, subcutaneous nodules, radiographic changes typical of rheumatoid arthritis, positive rheumatoid factor, and synovial fluid
Term
Rheumatoid nodules
Definition
also present in achilles tendon, metacarpophalangeal and interphalangeal joints, ischial tuberosities, and sacrum can also develop rheumatoid nodules
Term
Rheumatoid vasculitis
Definition
caused by necrotixing arteritis of small and medium size arteries, may be indistinguishable from polyarteritis nodosa
Term
Scleroderma
Definition
known as progressive systemic sclerosis, is a connective tissue disease characterized by cutaneous induration and thickening .
Term
Systemic scleroderma canbe classified as two distint entities,
Definition
Crest syndrome and diffuse scleroderma
Term
The Crest Syndrome
Definition
Calcinosis
Raynaud's phenomenon
Esophageal Dysmotility
Sclerodactyly
Telangiectasia
slowly progressive and therefore carries a more benign prognosis
Term
Morphea
Definition
is localized forms of scleroderma and not associated with systemic symptoms, characterized by localized plaques of indurated skin often surrounded by a vioilaceous halo
Term
Mixed Connective tissue disease
Definition
is a entity that combines features of sleroderma, lupus, and dermatomyositis
Term
Eosinophilic fasciitis
Definition
is extreme physical exertion or trauma often precedes the condition, which begins with painful swelling of the extremities
Term
Eosinophilia-myalgia syndrome
Definition
caused by ingesting oral L-tryptophan
Term
Cause of Vasculitis
Definition
at Mount Sinai Hospital Center:
Malignant-Medications
Strep-Serum Sickness
Henoch-Schonlein purpura-Hepatitis B
Connective tissue diseas-Cryoglobulinemia
Term
Henoch-Schonlein purpura
Definition
is form of vasculitis that most commonly occurs in children and young adults
Term
Henoch-Schonlein purpura
Definition
Gastrointestinal symptoms, abdominal pain, hematemesis, and melena, arthralgias and arthritis, symmetric palpable purpura of the lower extremities, and renal involvement as manifested by hematuria and proteinuria
Term
Behcet's disease
Definition
consist of a triad of oral, genital, and ocular lesions
Term
Behcet's disease
Definition
can lead to Pathergy that frequently apprears at sites of venipuncture or intravenous administraitonn
Term
Essential mixed cryoglobulinemia
Definition
arthralgias, skin lesions, and glomerulonephritis
Term
Plaque Psoriasis
Definition
is sharply demarcated erythematous scaling plaques, elbows and knees are typically involved, as are the scalp, intergluteal cleft, palms, soles, and genitals
Term
Guttate Psoriasis
Definition
occasionally develops after a streptococcal pharyngitis or other upper respiratory infection. Skin lesions are erythematous scaling, macules, papules that can become confluent to form plaque psoriasis
Term
Psoriatic Erythroderma
Definition
skin becomes red and scaly lead to hypotension, renal failure, loss of protein, iron deficiency anemia, leukocytosis because of increase cutaneous blood flow, and high output cardiac failure
Term
Pustular Psoriasis
Definition
charaterized by the development of sterile pustules either in psoriatic plaques or in previously uninvolved skin, open to palms and soles
Term
Pustular Psoriasis of Von Zumbusch
Definition
is a medical emergency characterized by abrupt onset of generalized pustules associated with fever and leukocytosis
Term
Pustular Psoriasis of Von Zumbusch
Definition
frequently occur after withdrawal of systemic steroids in a patient with pre-existing psoriasis.
Term
Impetigo Herperiformis
Definition
form of generalized pustular psoriasis, and results in severe constitutional symptoms, including dehydration, hypotension, renal failure, electrolyte imbalance, and hypocalcemia.
Term
Psoriatic arthritis
Definition
is asymmetric arthritic involving only two or three joints at a time, especially those of the fingers and toes, joint deformities identical to those seen in rheumatoid arthritis occur, but Rheumatoid factor is absent.
Term
Psoriatic arthritic
Definition
creating a "Pencil-in-cup," deformity, erosion of the middle phalanx and expansion of the base of the terminal phalanx.
Term
The most deforming type of psoriatic arthritis called
Definition
Arthritis mutilans
Term
In the severe cases of psoriatic arthritis resulting "telescoping of the digits" called
Definition
Opera-glass Deformity
Term
Psoriatic arthritis
Definition
have nail involved
Term
Reiter's syndrome
Definition
postdysenteric forms also occur, especially after infection with Shigella flexneri, salmonelli or Yersinia infection.
Term
Sarcoidosis
Definition
a multiorgan system disorder of unknown etiology, collecting of granuloma like a nodule, either caseating granulomatosis or non caseating granulomatosis
Term
Cause of Erythema Nodosum
Definition
Behcet's disease
Estrogens
Drugs
Recent infection
Enteropathies
Sarcoid
Tuberculosis
Term
Sarcoidosis
Definition
lead to ulcerations and may follow treatment with intralesional steroids and result from the cutaneous atrophy associated with corticosteroid therapy.
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