| Term 
 | Definition 
 
        | Oily with little water Best used to lubricate
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Emulsions of oil in water Easy to apply then vanish
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Water, alcohol or oily Convenient to apply, drying
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drying Vehicles are alcohol, propylene glycol, water
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | "Anti-itch" - pruritus MOA: soothes skin
 KIN: applied after bath, apply thin layer to dry skin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Pruritus Vistaril in adults; Benadryl in kids
 MOA: discourage the effort to scratch
 KIN: PO TID
 SE: sedation
 generally given for older people
 |  | 
        |  | 
        
        | Term 
 
        | Prednisone Methylprednisolone
 Dexamethasone
 |  | Definition 
 
        | Corticosteroids Acute tx of transient illness; Manage life-threatening dermatoses
 KIN: given as tapered dose
 |  | 
        |  | 
        
        | Term 
 
        | Diphenhydramine (Benadryl) Doxepin (Sinequan)
 |  | Definition 
 
        | Benadryl - elixir hs for kids Sinequan - for adults
 |  | 
        |  | 
        
        | Term 
 
        | Pimecrolimus 1% cream (Elidel) |  | Definition 
 
        | MILD TO MODERATE atopic dermatitis use when others have failed
 SE: pruritis, burning sensation
 BB: rare cases of cancer (skin, lymphoma)
 Avoid long term use and sunlight
 |  | 
        |  | 
        
        | Term 
 
        | Tacrolimus ointment (Prograf) |  | Definition 
 
        | MODERATE TO SEVERE atopic dermatitis use when others have failed
 SE: pruritis, burning sensation
 BB: rare cases of cancer (skin, lymphoma)
 Avoid long term use and sunlight
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Skin, vaginal infection; oral candidiasis PO & topical
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | DOC Oral esophageal candidiasis in AIDS pts
 Prophylaxis of vaginal candidiasis
 PO
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | DOC for mild to moderate comedonal & inflammatory acne MOA: modulate epithelial keratinization & inflam, dec formation of cmedones
 KIN: cream & gel, apply nightly, takes 6-12 weeks for full effect
 SE: photosensitivity, erythema, dryness
 Avoid excessive use and contact with mucous membranes
 |  | 
        |  | 
        
        | Term 
 
        | Benzoyl Peroxide 5 or 10% |  | Definition 
 
        | 1st line tx for mild to moderate noninflammatory acne MOA: penetrates striatum, contact sensitizer, bleaching agent
 KIN: applied QD, start c low concentration to decrease irritation
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | *Use if all other tx's fail* Severe recalcitrant nodular acne
 KIN: lesions get worse before it gets better
 SE: dryness of conjunctiva & lips, photosensitivity
 C/I: PG cat X
 2 pages of BB warnings
 All pts, HCP, & pharmacist must register c SMART system
 |  | 
        |  | 
        
        | Term 
 
        | 1st line therapy: Impetigo |  | Definition 
 
        | topical Mupirocin ointment TID for 7-10 days |  | 
        |  | 
        
        | Term 
 
        | 1st line therapy: Mild Cellulites |  | Definition 
 
        | broad-spectrum penicillin (amox/clav or dicloxacillin) |  | 
        |  | 
        
        | Term 
 
        | 1st line therapy: Pustular Infections |  | Definition 
 
        | warm compresses, topical tx with Mupirocin, gentamicin, bacitracin (systemic therapy may not be needed) |  | 
        |  | 
        
        | Term 
 
        | 1st line therapy: Paronychia |  | Definition 
 
        | systemic antibiotics (amox/clav, Cephalexin, dicloxacillin, erythromycin) |  | 
        |  | 
        
        | Term 
 
        | Mupirocin (Bactroban ointment) |  | Definition 
 
        | Rx only DOC for minor impetigo
 Tx skin infections 2' staph & various strep; gram + bacteria
 |  | 
        |  | 
        
        | Term 
 
        | Gentamicin (Garamycin cream or ointment) |  | Definition 
 
        | more effective against staph & beta-hemolytic strep than neomycin |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | topical - 1st line for HSV-1 oral - 1st line for VZV
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | oral - 1st line for herpes zoster |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1st line: moisturizers (emoillients - Eucerin, Lubriderm) & topical steroids 2nd line: reapplication of steroid after a weeks rest, possible add a vit D analog
 3rd line: referral to dermaologist
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Local anesthetic - esters Temporary relief of pain and itching - usually on mucus membranes; anal/vulvae pruritus, hemorrhoids
 MOA: prevent/suppress pain sensation by acting on peripheral sensory nerves
 KIN: topical or injection
 SE: sensitization
 C/I: app to throat may suppress swallowing, cough, gag reflex
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Corticosteroid Tx: responsive inflammatory conditions - allergic conjunctivitis, keratitis
 MOA: exert an anti-inflammatory action
 KIN: relieves itching, redness
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Mast cell stabilizer Tx: various inflammatory d/o - conjunctivitis, keratitis
 MOA: mast cell stabilizers that inhibit hypersensitivity reactions
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Beta-Blocker 1st line agent for primary open-angle glaucoma
 MOA: ophthalmic drops reduce IOP by decreasing production of aqueous humor
 SE: may cause systemic effects
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Prostaglandin analog Tx: glaucoma
 MOA: lower IOP by facilitating aqueous humor outflow by relaxing ciliary muscle
 SE: pigmentation of eyelid, blurred vision, local burning/stinging
 |  | 
        |  | 
        
        | Term 
 
        | Tetrahydrozoline (Visine) |  | Definition 
 
        | OTC antihistamine for relief of itching and redness - minor eye irritation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | DOC - amoxicillin resolves spontaneously in 80% of children
 |  | 
        |  | 
        
        | Term 
 
        | Otitis Externa "swimmer's ear" |  | Definition 
 
        | 1st line drug: fluoroquinolone (Cipro) |  | 
        |  |