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depression
unipolar depression
9
Psychology
12th Grade
06/18/2007

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Term
Unipolar depression
Definition
Depressed mood for at least 2 weeks plus at least 5 of the following:
Sleep changes
Aappetite changes
Death and suicidal thoughts
Concentration is effected
Loss of pleasure in activities
Energy loss and tiredness
Guilt and self-blame over real or imaginary events
Slowing down or constant restlessness
Term
unipolar: Reactive and endogenous
Definition
unipolar is the most common and severe type of depression.
Reactive - caused by an external factor such as an stressful life event.
endogenous - caused by internal factors from within the person.
PREVALANCE:
in GB 5% lifetime risk of developing unipolar depression
can appear at any age
appears cross culturally.
GENDER DIFFERENCES:
women 2-3 times more likely than men to suffer clinical depression
Term
Bipolar depression
Definition
depression followed by a manic episode
lasting at least a week.
SYMPTOMS:
increased pleasure in activities
racing ideas and thoughts
increase in goal directed activity.
PREVELANCE: 1% lifetime risk of devveloping this. tends to occur in early 20's
found equally in men and women
Term
Biological explanations
Genetics - evidence
Family studies
Definition
FAMILY STUDIES
Gershon - depression assessed in 1st degree relatives of patients with both uni and bi polar.rates of illness in these relatives were 2-3 times that in general population
EGELAND: studied the amish community in pennsylvania. Although community had relatively low rate of depression, one family had high livel of bipolar disorder. examination of their genes showed tht 2 marker genes on chromosome 11 appeared to be different
Term
Evaluation of family studies
Definition
The fact that depression runs in families e.g. between mother and daughter could be due to being brought up in the same environment or being brought up by a depressed parent.

The gene involved if it exists has not been identified and the finding by egeland has not been replicated.
Term
Genetics - twin studies.
Definition
findings show gentic factors are involved in boh types of depression.
Allen found that concordance rates for unipolar depression in mz twins was 40% and in DZ 11% and for bipolar disorder MZ 72% and DZ 14%.
however Beirut reported a heritability factorof between 36% and 44% showing that environmental factors played a role.
Term
evaluation of twin studies
Definition
Much of the evidence comes from twin studies in which the twins have not been reared apart so the higher concordance rate could be due to environmental factors.
Term
adoption studies
Definition
able to seperate genetic and environmental factors.
Wenders found that biological relatives of depressives who had been adopted were 8 times more likely to suffer depression than the adoptive relatives.
Term
I love andy volwes
Definition
I am mikey b
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