Term
|
Definition
1) More common in whites
2) Ages 20-50
3) Northern European/North America |
|
|
Term
|
Definition
1) more than 1 episode of dysfunction
2) white matter lesions in more than 1 area of CNS |
|
|
Term
| What are some typical clinical neurologic findings with MS? (4) |
|
Definition
1) optic neuritis
2) internuclear opthalmoplegia
3) heat sensitivity
4) Lhermitte symptom |
|
|
Term
| What are the two clinical courses of MS? |
|
Definition
1) relapsing/remitting: neurological deficit episodes more frequent w/time
2) Progressive Pattern: steady accumulation of deficits |
|
|
Term
| What is the single most useful test for diagnosing MS? |
|
Definition
| MRI - also for follow-up/management |
|
|
Term
| What are 2 characteristic findings in the CSF with MS? |
|
Definition
1) intrathecal synthesis of immunoglobulins
2) oligoclonal bands |
|
|
Term
| What med is used for acute relapses/exacerbations of MS? |
|
Definition
| High-dose corticosteroids |
|
|
Term
| What percent of brain function is lost every 5 years w/MS? Normally? |
|
Definition
1) MS-4.5% untreated
2) 1.5% normally |
|
|
Term
| What do use to prevent relapses of MS? |
|
Definition
|
|
Term
| What med is effective in aggressive relapsing MS and reduces symptoms by 67%? |
|
Definition
|
|
Term
| What infections are very common in women with MS? |
|
Definition
|
|
Term
| unilateral vision loss and retrobulbar pain with eye movement is associated with what? |
|
Definition
|
|
Term
| Acute disseminated encephalomyelitis is usually preceded by what? |
|
Definition
|
|
Term
| What is the initial presenting symptom in 20% with MS? |
|
Definition
|
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