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Dartmouth Antibiotics
Dartmouth Antibiotics
35
Medical
Graduate
04/07/2009

Additional Medical Flashcards

 


 

Cards

Term

antimetabolites

 

What are the three?

Definition

Sulfanamides

Trimethoprim

Isoniazid

Term

antimetabolite

 

Sulfanamides

 

Function?

Definition
stop DNA syn via folic acid
Term

antimetabolites

 

Trimethoprim

 

Function?

Definition
inhibits dihydrofolate reductase
Term

Antimetabolites

 

Isoniazid

 

Function?

Definition

stops M. tuberculosis via mycolic acid

(inhibits InhA an elongation enzyme)

Term

Bactrim

 

What is it and what is it good for?

 

 

Definition

A combo of trimethoprim and sulfa

 

 

good for uti

Term

What are some sulfas good for and why?

 

ie. Bactrim

Definition

UTI

 

that is where they are concentrated

Term

Inhibitors of wall synthesis

 

limited spectrum

 

what are they?

Definition

penicillin G

 

Penicillin V

Term

Inhibitors of wall synthesis

 

broad spectrum

 

what are they?

Definition

Ampicillin

 

Amoxicillin

Term

Inhibitors of wall synthesis

 

extended spectrum

 

what are they?

Definition

Tricarcillin

 

Piperacillin

Term

Inhibitors of wall synthesis

 

penicillinase resistant

 

what are they?

Definition

Methicillin

 

Oxacillin

Term

Inhibitors of wall synthesis

 

limited spectrum

 

what do they kill?

Definition
G+ and G- Cocci
Term

Inhibitors of wall synthesis

 

broad spectrum

 

what do they kill?

Definition
most G+ and G- enteric bacilli
Term

Inhibitors of wall synthesis

 

extended spectrum

 

what do they kill?

Definition

will kill most G- bacilli less effective against G+

effective against pseudomonas

Term

Inhibitors of Cell Wall

 

What penicillins are resistant to penicillinase?

Definition

Methicillin

 

Oxacillin

 

called antistaphy antiboitics

Term

Inhibitors of cell wall

 

Name a 1st generation Cephalosporin

Definition
cefazollin
Term

Inhibitors of cell wall

 

Name a 2nd generation Cephalosporin

Definition
cefuroxime
Term

Inhibitors of cell wall

 

Name a 3rd generation Cephalosporin

Definition

ceftriaxone

 

cerftazdime

Term
what does ceftriaxone and cerftazdimen kill?
Definition

most G-

 

with

ceftriaxone against Pseudomonas

 

cerftazdime in CNS

Term
what does cerfazolin kill?
Definition
G+ and some G- enteric
Term
what does cerfuroxime kill?
Definition
better at G- and some G+
Term
name a monobactam?
Definition
aztreonam
Term

what does aztreonam kill

 

 

 

Definition

 

aerobic G- that includes pseudomonus

Term
name a carbapenem
Definition
imipenem
Term
what does imipenem kill
Definition

broadest antimicrobial spectrum

 

 

Term
name two beta lactamase inhibitors
Definition

Clavulanic acid

 

sulbactam

Term
What is bactim
Definition
combo of trimethoprim and sulfamethoxazole used in uti
Term
What is augmentin
Definition
clavulanic acid and ammoxicillin
Term
What does vancomycin kill
Definition

G+

 

used for systemic of enteric because not absorbed well, and Clostridium enterocolitis.

 

also only drug available for multiply resistant enterococcus and MRSA

Term
what are vancomycin side effects
Definition
toxic, kidneys and hearing
Term
what does Teicoplanin do
Definition
acts like vancomycin with longer half life
Term
 what is Cycloserine and what does it kill
Definition

D alanine analog inhibits wall synthesis

 

tb very toxic

Term
What does bacitracin kill
Definition

G+

 

topical only

Term
What does polymyxins kill
Definition
G- enterobacilli
Term
What does daptomycin kill
Definition
multiple resistant G+
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