Term
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Definition
Source:
Macrophages, monocytes, dendritic cells
Action:
Activate macrophages; Lower BP; induce shock; pyrogenic |
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Term
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Definition
Source:
ThP, Th0, Th1
Receptor:
CD132, CD122
Action:
Clonal expansion and IL-2R expression; Enhances NK cytotoxicity; pCTL->CTL (cytotoxic leukocyte) |
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Term
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Definition
Source:
All T-cells
Receptor:
CD131
Action:
Pluripotent stem cells -> Myeloid progenitor cells (along with GM-CSF); Pluripotent stem cells -> Lymphoid cells |
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Term
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Definition
Source: Mast Cells; Th0; Th2
Receptor: CD 132
Action:
Isotype switching B cells to M, G and D; Downregulates Th1; inhibits iNOS, Th0->Th2 |
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Term
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Definition
Source: Mast Cells; Th2
Receptor: CD131
Action:
Myeloid cells->eosinophils; Chemotactic for eosinophils; Activation of eosinophils; IgG->IgE |
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Term
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Definition
Source:
Macrophages; Th2
Receptor:
CD130
Action:
Stimulates C-reactive protein; Inflammation |
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Term
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Definition
Source:
Bone Marrow Stromal Cells
Receptor: CD132
Action: Lymphoid progenitor cells -> B-cells, T-cells and NKs; T-cell development in thymus |
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Term
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Definition
Source:
Macrophages; Endothelial cells
Action: Chemotactic for neutrophils |
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Term
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Definition
Source: CD4+
Receptor: CD132
Action: Prevents apoptosis |
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Term
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Definition
Source:
Monocytes, Th2
Action:
Inhibition of IL-12, IFNy, Th1 and iNOS; Anti-inflammatory |
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Term
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Definition
| Action: Bone cell proliferation and differentiation, |
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Term
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Definition
Source: Macrophages, dendritic cells
Action: Activates NK cells to secrete IFNy |
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Term
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Definition
Source: Th2
Action: IgE; Anti-inflammatory; Anti-parasitic |
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Term
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Definition
Source: Leukocytes
Action: Produces chemicals to interfere with viral replication |
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Term
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Definition
Source: NK cells, Th0, Th1
Action: Activates iNOS, NADPH oxidase; inhibits Th2; Th0->Th1; pCTL->CTL; Upregulates MHC an macrophages |
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