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Cytokines
Cytokines
20
Biology
Professional
07/21/2011

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Cards

Term
What secretes IL-1?
Definition
Macrophages
Term
What is the function of IL-1?
Definition
  • Produce fever
  • Stimulate T helper cells
  • Stimulates osteoclasts
Term
What secretes IL-2?
Definition
TH-1 cells
Term
What is the function of IL-2?
Definition
  • Stimulates other T and B cells
Term
What secretes IL-3?
Definition
  • T helper cells
  • NK cells
Term
What is the function of IL-3?
Definition
  • Stimulates hematopoietic cells
Term
What secretes IL-4?
Definition
TH-2 cells
Term
What is the function of IL-4?
Definition
Stimulates B cells and IgE
Term
What secretes IL-5?
Definition
  • TH-2 cells
  • Macrophages
Term
What is the function of IL-5?
Definition
  • Stimulates B cells and IgA
  • Stimulates Eosinophils
Term
What secretes IL-6?
Definition
  • T cells
  • Macrophages
Term
What is the function of IL-6?
Definition
  • Produce fever
  • Stimulates B cells
  • Stimulates TH cells
  • Stimulates osteoclasts
Term
What secretes IL-8?
Definition
  • Monocytes
  • Macrophages
Term
What is the function of IL-8?
Definition
Chemotaxis of PMN's "Sticky"
Term
What secretes IL-10?
Definition
TH-2 cells
Term
What is the function of IL-10?
Definition
Inhibit TH-1 cells
Term
What secretes IL-12?
Definition
  • Monocytes
  • Macrophages
Term
What is the function of IL-12
Definition
Stimulates TH-1 cells
Term
What secretes TGF-beta?
Definition
  • Monocytes
  • Macrophages
  • T cells
  • B cells
Term
What is the function of TGF-beta?
Definition
  • The "Anti-cytokine"
  • Stimulates collagen formation and wound healing
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