Term
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Definition
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Term
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Definition
| lymphocyte activation, macrophage activation, leukocyte/endothelial adhesion, pyrexia, acute phase proteins |
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Term
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Definition
| t-cell proliferation & differentiation, activation of cytotoxic lymphocytes & macrophages |
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Term
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Definition
| multilineage colony stimulation factor |
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Term
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Definition
| B-cell growth factor, isotype selection, IgE, IgG2, IgG4, IgA, suppresses cell mediated immunity & production of IgG1 & IgG3 |
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Term
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Definition
| B-cell growth & differentiation, IgA selection |
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Term
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Definition
| B-cell differentiation, induces acute phase proteins |
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Term
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Definition
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Term
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Definition
| inhibition of cytokine synthesis? Cytokine released by CD4 T helper 2 cells & regulatory t cells. Promotes development of t helper 2 cells & inhibit macrophage activation |
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Term
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Definition
| secreted by macrophages to activate NK cells or T helper 1 cells |
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Term
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Definition
| B cell growth & differentiation, inhibits pro-inflammatory cytokine production |
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Term
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Definition
| release of IL-6, IL-8, G-CSF, PGE2, enhances ICAM-1, stimulates fibroblasts to sustain CD34+ PROGENITORS |
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Term
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Definition
| MHC class I induction, antiviral state, stimulation of NK cells, anti-proliferative, stimulates IL-12 production & T helper 1 |
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Term
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Definition
| MHC class I & II induction, MÆ activation, endothelial cell/lymphocyte adhesion, MÆ cytokine synthesis, antiviral state, anti-proliferative t helper 1 cells |
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Term
| Tumor necrosis factor-α (TNF-α) |
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Definition
| activation of MÆ, granulocytes & cytotoxic cells, leukocyte endothelial cell adhesion, cachexia, pyrexia, induction of acute phase proteins, stimulation of angiogenesis, enhanced MHC class I production |
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Term
| Tumor Necrosis factor –β (TNF-β) |
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Definition
| lymphotoxin, produced by t lymphocytes that inhibits growth of tumors & blocks transformation of cells |
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Term
| Transforming growth factor-β (TGF-β) |
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Definition
| downregulates inflammatory cytokine production, promotes wound healing responses & scar tissue, growth inhibition |
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Term
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Definition
| binds to CCR7. Acts toward dendritic cells & t lymphocytes. Mediates homing of lymphocytes to 2° lymphoid organs |
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Term
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Definition
| secreted by stromal cells & dendritic cells in 2° lymphoid tissues, attract luekocytes & dendritic cells to the tissue |
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Term
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Definition
| secreted by mature dendritic cells in 2° lymphoid tissues, which specifically attract naïve T cells. |
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Term
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Definition
| produced by t helper 1 cells, guides phagocytes b/w the endothelial cells into the infected area. |
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