Term
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Definition
Secreted by macrophages.
Fever, acute inflammation, adhesion molecule expression in endothelium, chemokine secretion to recruit leukocytes |
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Term
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Definition
Secreted by macrophages and TH cells.
Fever, stimulates production of acute-phase proteins. |
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Term
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Definition
Secreted by macrophages.
Major chemotactic factor for neutrophils |
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Term
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Definition
Secreted by macrophages and B cells.
Induces differentiation of T cells into TH1, activates NK cells. |
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Term
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Definition
Secreted by macrophages.
Mediates septic shock, activates endothelium, causes leukocyte recruitment and vascular leak |
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Term
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Definition
Secreted by all T cells
Supports growth and differentiation of bone marrow stem cells |
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Term
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Definition
Secreted by TH1 cells.
Stimulates growth of helper and cytotoxic T cells |
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Term
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Definition
Secreted by TH1 cells
Activates macrophages and TH1 cells, suppresses TH2 cells, has antiviral and antitumor properties, increases MHC I and II expression on APCs |
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Term
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Definition
Secreted by TH2 cells.
Induces differentiation into TH2, promotes growth of B cells, enhances class switching to IgE and IgG |
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Term
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Definition
Secreted by TH2 cells
Promotes differentiation of B cells, enhances class switch to IgA, stimulates growth and differentiation of eosinophils |
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Term
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Definition
Secreted by TH2 cells and Tregs.
Modulates inflammatory response (similar to TNF-alpha), inhibits actions of activates T cells and TH1, activates TH2 |
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Term
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Definition
| Inhibits viral protein synthesis, activates NK cells |
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Term
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Definition
| Inhibits viral protein synthesis, activates NK cells |
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Term
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Definition
Surface protein on T cells
Binds antigen-MHC complex |
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Term
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Definition
Surface protein on T cells
Associated with TCR for signal transduction |
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Term
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Definition
Surface protein on T cells
Binds B7 on APC |
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Term
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Definition
Surface protein on B cells
Binds antigen |
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Term
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Definition
| Surface protein on helper T cells |
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Term
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Definition
| Surface protein on cytotoxic T cells |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| B cells, receptor for Epstein-Barr virus |
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Term
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Definition
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Term
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Definition
| Surface protein on B cells and other APCs |
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Term
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Definition
Surface protein on B cells, APCs
Binds CD28 on T cells |
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Term
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Definition
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Term
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Definition
Macrophages
Enhances phagocytosis |
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Term
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Definition
Macrophages
Enhances phagocytosis |
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Term
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Definition
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Term
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Definition
NK cells
Unique marker for NK |
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Term
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Definition
| All cells except erythrocytes |
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