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CYP Inducers / Inhibitors
Drug Metabolism: CYP Inducer / Inhibitors
49
Pharmacology
Professional
08/31/2011
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Term
rifampin
 Definition
INDUCER: 1A2 - 2C9 - 3A4.5.7
Term
carbamazepine
 Definition
INDUCER: 1A2 - 2C9 - 3A4.5.7
Term
phenobarbital
 Definition
INDUCER: 1A2 - 2C9 - 3A4.5.7
Term
ritonavir
 Definition
INDUCER: 1A2 - 3A4.5.7 & INHIBITOR: 2D6 - 3A4.5.7
Term
tobacco
 Definition
INDUCER: 1A2
Term
phenytoin
 Definition
INDUCER: 2C9 - 2C19 - 3A4.5.7
Term
secobarbital
 Definition
INDUCER: 2C9
Term
methadone
 Definition
INDUCER?: ?.2D6.?
Term
ethanol
 Definition
INDUCER: 2E1
Term
isoniazid
 Definition
INDUCER: 2E1 & INHIBITOR: 2C9 - 2C19
Term
St. Jon's wort
 Definition
INDUCER: 3A4.5.7
Term
troglitazone
 Definition
INDUCER: 3A4.5.7
Term
rifabutin
 Definition
INDUCER: 3A4.5.7
Term
antiretroverials
 Definition
Inducers & Inhancers
Term
amiodarone
 Definition
INHIBITOR: 1A2 (str) - 2C9 - 2C19 - 2D6 (wk) - 3A4.5.7
Term
cimetidine
 Definition
INHIBITOR: 1A2 - 2C19 - 2D6 (wk) - 2E1 - 3A4.5.7 (wk)
Term
fluoxetine
 Definition
INHIBITOR: 1A2 - 2C9 - 2C19 - 2D6 (str)- 3A4.5.7
Term
ketoconazole
 Definition
INHIBITOR: 1A2 - 3A4.5.7 (str)
Term
ciprofloxacin
 Definition
INHIBITOR: 1A2 (fluoroquinolone)
Term
enoxacin
 Definition
INHIBITOR: 1A2 (fluoroquinolone)
Term
norfloxacin
 Definition
INHIBITOR: 1A2 (fluoroquinolone)
Term
fluvoxamine
 Definition
INHIBITOR: 1A2 - 2C19 - 3A4.5.7
Term
zileuton
 Definition
INHIBITOR: 1A2
Term
omepraxole
 Definition
INHIBITOR: ?.2C9.? - 2C19
Term
fluconazole
 Definition
INHIBITOR: 2C9 - 2C19 - 3A4.5.7 (less)
Term
zafirlukast
 Definition
INHIBITOR: 2C9
Term
voriconazole
 Definition
INHIBITOR: 2C9 - 2C19 3A4.5.7
Term
itraconazole
 Definition
INHIBITOR: 3A4.5.7 (str)
Term
zafirlukast
 Definition
INHIBITOR: 2C9
Term
iansopraxole
 Definition
INHIBITOR: 2C19
Term
modafinil
 Definition
INHIBITOR: 2C19
Term
ticlopidine
 Definition
INHIBITOR: 2C19
Term
bupropion
 Definition
INHIBITOR: 2D6 (str)
Term
clomipramine
 Definition
INHIBITOR: 2D6
Term
duloxetine
 Definition
INHIBITOR: 2D6
Term
paroxetine
 Definition
INHIBITOR: 2D6
Term
haloperidol
 Definition
INHIBITOR: 2D6
Term
quinidine
 Definition
INHIBITOR: 2D6
Term
disulfiram
 Definition
INHIBITOR: 2E1
Term
nicardipine
 Definition
INHIBITOR: 3A4.5.7
Term
clarithromycin
 Definition
INHIBITOR: 3A4.5.7 (str)
Term
eryhtromycin
 Definition
INHIBITOR: 3A4.5.7 (orange/medium)
Term
troleandomycin
 Definition
INHIBITOR: 3A4.5.7
Term
azithromycin
 Definition
INHIBITOR: NONE!! Especially not 3A4.5.7
Term
nefaxodone
 Definition
INHIBITOR: 3A4.5.7 (str)
Term
fluvoxamine
 Definition
INHIBITOR: 3A4.5.7
Term
grapefruit juice
 Definition
INHIBITOR: 3A4.5.7 (orange/medium)
Term
diltiazem
 Definition
INHIBITOR: 3A4.5.7 (orange/medium)
Term
verapmail
 Definition
INHIBITOR: 3A4.5.7 (orange/medium)
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