Shared Flashcard Set

Details

CYP enzymes
substrates, inducers, inhibitors
12
Medical
Graduate
07/15/2012

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Cards

Term
Substrates include:
Acetaminophen
theophylline*
warfarin*
Definition
1A2
Term
Inducers include:
benzo from tobacco smoke
Definition
1A2
Term
Inhibitors include:
Cimetidine, grapefruit juice, macrolides
Definition
1A2
Term
Substrates include:
Celecoxib, ibuprofen, steroids, phenytoin, warfarin (s)
Definition
2C9
Term
Inducers include:
Barbituates (phenobarbitol), rifampin
Definition
2C9
Term
Inhibitors include
Amiodarone, cimetidine, SSRIs
Definition
2C9
Term
Substrates include:
Acetaminophen, ethanol (minor pathway)
Definition
2E1
Term
Inducers include:
Ethanol
Definition
2E1
Term
Inhibitors include:
Disulfram
Definition
2E1
Term
Substrates include:
Acetaminophen*, amiodarone, cyclosporine, eryhtromycin, lovastatin*, HIV protease inibitors*, many others
Definition
3A4
Term
Inducers include:
Barbituates*, glucocorticoids, rifampin*, phyenytoin*
Definition
3A4
Term
Inhibitors include:
Clarithromycin, eryhromycin*, grapefruit juice* (furancoumarins), cimetidine, ritonavir*, fluconAZOLE*, itraconAZOLE*
Definition
3A4
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