Term
|
Definition
•50 u/kg
•For acute myocardial infarction (AMI) 5000u loading and 1000 u/hr |
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Term
|
Definition
•.25 mg/kg bolus
•Then .125 mcg/kg/min for MI
•For PCI post, 10 mcg/kg/min for 12 hours |
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Term
| Tirofiban HCL (Aggrastat) |
|
Definition
•Initial dose of 0.4 mcg/kg/min for 30 minutes
•Followed by 0.1 mcg/kg/min for 48 to 108 hours or 12 – 24 hours after coronary intervention |
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Term
|
Definition
•Initially, 1 mg/kg IV bolus just before PCI
•Infusion at 2.5 mg/kg/hr for 4 hours
•Administer another IV infusion at 0.2 mg/kg/hr for up to 30 hours as needed
•Store prepared solution for up to 24 hours at 36 to 46 degrees Fahrenheit
•Give with 325 mg of aspirin |
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Term
|
Definition
•Begin infusion of 25 mcg/kg/min and administer bolus dose of 350 mcg/kg (over 3 to 5 minutes)
•ACT should be checked 5 to 10 minutes after bolus
•Proceed with procedure if ACT is > 300 seconds
•ACT < 300 seconds: give an additional 150 mcg/kg bolus and increase infusion rate to 30 mcg/kg/min (recheck ACT in 5 to 10 minutes)
•ACT > 450 seconds: decrease infusion rate to 15 mcg/kg/min (recheck ACT in 5 to 10 minutes)
•Once at therapeutic ACT (300 to 450 seconds), infusion should be continued at this dose for the duration of the procedure
•Reduce dosage to 0.5 mcg/kg/min in hepatic impairment
•Impending abrupt closure, thrombus formation during PCI, or inability to achieve ACT > 300 seconds: an additional bolus of 150 mcg/kg, followed by an increase in infusion rate to 40 mcg/kg/min may be administered |
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Term
| Integrilin (Eptifibatide) |
|
Definition
•For MI 180 mcg/kg bolus then 2 mcg/kg/min for 72 hours
•For PCI 135 mcg/kg bolus then .5 mcg/kg/min |
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Term
|
Definition
| •1 mg/kg BID with ASA for 2 - 8 days |
|
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Term
|
Definition
•1 mg neutralizes 100 units of heparin
•50 mg max in a 10 minute period |
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Term
|
Definition
•Loading 6 - 10 mg over 1 - 2 min
•60 mg over the first hour
•Second and third hours 20 mg each
•Weight < 65 kg give 1.25 mg/kg over three hours |
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Term
|
Definition
•10 units over 2 min
•Repeat 10 unit in thirty minutes |
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Term
|
Definition
•Analgesic/antipyretic: 325 - 650 mg PO q 4 hours as needed
•Acute MI: 325 mg (or 4 x 81 mg chewable tablets to facilitate sublingual absorption and to expedite antiplatelet activity)
•Thromboembolic disorders: 325 - 650 mg PO QD or BID
•MI prophylaxis: 81 - 325 mg PO QD |
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Term
|
Definition
•75 mg PO QD is recommended
•For ACS with or without PCI, load with 300 mg and then continue with 75 mg daily |
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Term
|
Definition
•Hypertension
•PO: 5 mg/day; may increase to 10 to 40 mg/day in 1-2 divided doses
•IV: 1.25 mg slow IV push over 5 minutes every 6 hours; may give up to 5 mg every 6 hours in hypertensive emergencies
•CHF: 2.5 mg PO QD or BID; may increase up to 5 to 20 mg/day in 1 to 2 divided doses (max of 40 mg/day |
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