| Term 
 
        | Antihistamines Blk resp histamine; capill constrict, smooth muscles relax, ↓HR
 |  | Definition 
 
        | Allegra, Benadryl Claritin, Zyrtec
 Drowsy,no hvy machinery/haz act
 |  | 
        |  | 
        
        | Term 
 
        | Decongestants ↓nasal membr; relieve nasal stuffiness
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Antitussives ↓cough reflex in CNS
 |  | Definition 
 
        | Tessalon Perles Robitussin DM
 Codeine (opioids) ↓RR, ↓HR, const
 |  | 
        |  | 
        
        | Term 
 
        | Expectorant (Mucolytics) Liquefy/thin resp secretions
 |  | Definition 
 
        | Guaifenesin (Robitussin) Mucinex
 Mucomyst
 |  | 
        |  | 
        
        | Term 
 
        | Beta-Adrenergic Agonist Relax/dilate bronchi/bronchioles
 RELIEF OF ACUTE SYMPTOMS
 |  | Definition 
 
        | Albuterol, liq, inh, SQ, IM, IV Levalbuterol, inh
 Terbutaline, IV
 h/a, tremors, ↑HR, ↑ BP
 Inh best route (3-5 min)
 |  | 
        |  | 
        
        | Term 
 
        | Xanthine Derivatives Relax/dilate bronchi/bronchioles
 MAINTENANCE DRUG
 |  | Definition 
 
        | Theophylline, PO, inh, IV(severe) 10-20mcg/ml
 avoid foods ↑xanthines (coffee, cola, chocolate); toxicity (restless, agitated, insomnia, chest pain)
 |  | 
        |  | 
        
        | Term 
 
        | Corticosteroids Stabilize rel histamine
 ↓inflam, edema, secretions
 MAINTENANCE DRUG
 |  | Definition 
 
        | Methylprednisone Beclomethasone
 Fluticasone
 |  | 
        |  | 
        
        | Term 
 
        | Leukotriene Receptor Antagonists Block Leukotriene
 Prevent bronchoconstriction
 MAINTENANCE DRUG
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Mast Cell Stabilizers Prevent rel of substcause bronchoconstr
 MAINTENANCE DRUG
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Loop Diuretic Inhibit Na reabsp ↑Loop of Henle
 |  | Definition 
 
        | Lasix hyponatremia, hypokalemia, orthostatic hypotension
 |  | 
        |  | 
        
        | Term 
 
        | Thiazide Diuretic Inhibit Na reabsp ↑ Loop of Henle/ distal tubules
 |  | Definition 
 
        | Chlorothiazide hyponatremia, hypokalemia, orthostatic hypotension
 |  | 
        |  | 
        
        | Term 
 
        | Potassium Sparing Inhibit Na reabsp distal tubules/ collecting ducts
 |  | Definition 
 
        | Spironolactone hyponatremia, hyperkalemia, orthostatic hypotension
 |  | 
        |  | 
        
        | Term 
 
        | Osmotic shift in fl to move into renal tubules from surrounding tissue
 |  | Definition 
 
        | Osmitrol circulatory overload
 |  | 
        |  | 
        
        | Term 
 
        | Antispasmodics Cholinergic Blocking Agents
 Inhibit bladder contractions, delay urge to void
 |  | Definition 
 
        | Ditropan Detrol
 anticholinergic effects
 safety, pill fragments in stool
 |  | 
        |  | 
        
        | Term 
 
        | Analgesics Relieve pain w/ irritation ↓GU tract
 |  | Definition 
 
        | Pyridium orange urine/ tears
 stain fabric/contacts
 |  | 
        |  | 
        
        | Term 
 
        | Anti-Infectives (Uroseptics) Treat UTI; Interfere w/ bacterial mult in urine
 |  | Definition 
 
        | Nitrofurantoin GI Upset, ↑fl, perineal hyg, take ALL
 |  | 
        |  | 
        
        | Term 
 
        | ACE Inhibitors Inhibits angiotensin I to II to rennin (↓peripheral arterial resistance)
 |  | Definition 
 
        | Captopril Enalapril
 dizzy, cough, salty/metallic taste
 |  | 
        |  | 
        
        | Term 
 
        | Antihypertensive Agents Diuretic
 Inhibit Na reabrp ↑ Loop of Henle
 |  | Definition 
 
        | Lasix hyponatremia, hypokalemia
 |  | 
        |  | 
        
        | Term 
 
        | Beta Blockers Inhibit sympathetic stim
 (↓BP, ↓HR)
 |  | Definition 
 
        | Atenolol Metoprolol
 h/a, hypotension (orthostatic)
 |  | 
        |  | 
        
        | Term 
 
        | Vasodilators Relax peripheral vascular sm muscles
 |  | Definition 
 
        | Hydralazine h/a, hypotension (orthostatic)
 |  | 
        |  | 
        
        | Term 
 
        | Positive Inotropic Agents Treat CHF aka Cardiac Glycosides
 |  | Definition 
 
        | Digoxin 0.5 – 2.0 ng/L
 Antidote = Digibind
 Interacs: K+ sparing diuretics & Beta Blockers
 Adverse (toxicity): N/V, restless/ irritable, confused, disoriented, bl vision, white halos on dark objects, arrhythmias
 Ck HR: ↓60 or ↑100, DO NOT GIVE MED
 Monitor Digoxin & K+ lvls
 |  | 
        |  | 
        
        | Term 
 
        | Antidysrhythmic Agents Treat dysfunctional heart rhythms
 Treat ab electrophysiologic funct, Class I, Ia, Ib, Ic, II, III, & IV
 |  | Definition 
 
        | Lidocaine Adenosine
 Sotolol
 h/a, dizzy, bl vision; emer equip avail
 Monitor ECG, electrolyte lvl
 |  | 
        |  | 
        
        | Term 
 
        | Antiangina Agents Nitrates
 IMMEDIATE RELIEF
 |  | Definition 
 
        | Nitroglycerin SL (preferred), PO, oint, patches, translingual spray, IV
 h/a, hypotension
 |  | 
        |  | 
        
        | Term 
 
        | Antiangina Agents Beta-Blockers
 ↓HR & ↓force contraction
 LONG TERM PREVENTION
 |  | Definition 
 
        | Metoprolol h/a, hypotension
 |  | 
        |  | 
        
        | Term 
 
        | Antiangina Agents Ca Channel Blockers
 LONG TERM PREVENTION
 |  | Definition 
 
        | Procardia Norvasc
 Cardizem
 h/a, hypotension
 |  | 
        |  | 
        
        | Term 
 
        | Anticoagulant: Parenteral Inhibit clot formation; binds to antithrombin III-turn off clot factors
 |  | Definition 
 
        | Heparin, IV (aPPT/PTT) Enoxaparin, SQ
 Antidote: Protamine Sulfate
 Bleeding; Int w/other anticoagulants
 |  | 
        |  | 
        
        | Term 
 
        | Anticoagulant: Oral Inhibit clot, Vit K clot factors
 (II, VII, IX, X)
 |  | Definition 
 
        | Coumadin (PT/INR) Antidote: Vit K
 Bleeding;Int w/other anticoagulants
 |  | 
        |  | 
        
        | Term 
 
        | Antiplatelet Block cyclooxygenase→inhibits thromboxaneprevent→formation platelets
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Thrombolytic Convert plasminogen to plasmin, which lyse clots
 |  | Definition 
 
        | Streptase Alteplase
 Bleeding
 |  | 
        |  | 
        
        | Term 
 
        | Fibrin Agents aka Antifibrinolytic Agents
 Promote clot by inhibiting fibrin lyses
 |  | Definition 
 
        | Amicar Blood clot (thrombus)
 |  | 
        |  | 
        
        | Term 
 
        | Cholesterol Synthesis Inhibitors HMG-CoA Reductase Inhibitors or “statins”; Inhibit cholesterol synthesis (↓ production)
 |  | Definition 
 
        | Atorvastatin Rosuvastatin
 GI disturbance, ↑liver enzyme lvls, rhabdomyolysis
 |  | 
        |  | 
        
        | Term 
 
        | Bile Acid Sequestrants ↓absp bile acids intestine→liver use cholesterol to make more bile (↓absp)
 |  | Definition 
 
        | Cholestyramine GI disturbance, ↑liver enzyme lvls, rhabdomyolysis
 |  | 
        |  | 
        
        | Term 
 
        | Fibrinic Acid Derivatives ↓absp/production, ↓triglyceride
 |  | Definition 
 
        | Gemfibrozil GI disturbance, ↑liver enzyme lvls, rhabdomyolysis
 |  | 
        |  | 
        
        | Term 
 
        | Niacin ↓metabolism of cholest & triglycerides
 |  | Definition 
 
        | Niacin (B3) GI disturbance, ↑liver enzyme lvls, rhabdomyolysis
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | confusion and impaired thought processes (Potassium Supplements) |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | cardiac arrhythmias (Kayexalate) |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | confusion, tachycardia, irritability |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | edema, thirst, convulsions, coma |  | 
        |  |