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CV/Autacoids
Assessment 1 -block 2
76
Pharmacology
Graduate
08/20/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
PGE1
Definition
cardio, GI, gyne, maintain patent infant DA, urology
Term
PGI2
Definition
cardio, anticoagulant, GI, pulmonary HTN, infant DA,
Term
PGF2α
Definition
gyne, ophthalmology
Term
PGE2
Definition
gyne,
Term
15-methyl-PGF2α
Definition
gyne
Term
PGI2 analogs
Definition
pulm HTN,
Term
latanoprost, bimatoprost, travoprost
Definition
PGF2α ophthalmology
Term
Aprotonin
Definition
hemostatics: given to decrease bleeding
Term
Nesiritide
Definition
CHF (inotropes autacoid, BNP analog)
Term
Ambrisentan
Definition
endothelin receptor antagonist
Term
Acetazolamide
Definition
carbonic anhydrase inhibitor (PCT)
Term
Furosemide
Definition
HTN, CHF (loop diuretic)
Term
Bumetanide
Definition
HTN (loop diuretic)
Term
Torsemide
Definition

HTN (loop diuretic)

can cause hypokalemia

Term
Mannitol
Definition
osmotic diuretic
Term
HCTZ
Definition

HTN (thiazide, DCT)

can lead to hypokalemia

 

Term
Chlorathiadone
Definition

Thiazide like Diuretic (DCT)

can cause hypokalemia

Term
Metolazone
Definition

HTN, CHF (thiazide like DCT)

can cause hypokalemia

10X potent as HCTZ

Term
Quinothazone
Definition
thiazide diuretic, DCT
Term
Indapamide
Definition

HTN (thiazide diuretic DCT)

20X potent HCTZ

Term
Spironolactone
Definition

HTN, CHF (DCT, K+ sparing)

aldosterone antagonist

Term
Eplerenone
Definition
HTN, CHF (DCT K+ sparing aldosterone antagonist)
Term
Amiloride
Definition

HTN (DCT K+ sparing)

not an aldosterone antagonist

Term
Triamterene
Definition

HTN (DCT K+ sparing)

not an aldosterone antagonist

Term
Argenine vasopressin
Definition

ADH agonist, collecting duct

binds V1 → vasoconstriction

Term
Desmopressin
Definition

ADH agonist collecting duct

binds V2 → aquaporin channels

Term
Demeclocyclin
Definition

ADH antagonist, collecting duct

treats SIADH

Term
Clonidine
Definition
HTN (centrally α2 agonist)
Term
Guanabenz
Definition
HTN (centrally α2 agonist)
Term
Guanfacine
Definition
HTN (centrally α2 agonist)
Term
Resperine
Definition
HTN (inhibits intracellular NE packaging)
Term
Phenoxybenzamine
Definition
HTN (α1, α2 irreversible antagonist)
Term
Prazosin
Definition
HTN (α1 antagonist)
Term
Doxazosin
Definition
HTN (α1 antagonist)
Term
Terazosin
Definition
HTN (α1 antagonist)
Term
Propanolol
Definition
HTN (β1, β2 antagonist)
Term
Carvedilol
Definition
HTN, CHF (β1, β2 antagonist)
Term
Pindolol
Definition
HTN (β1, β2 antagonist)
Term
Timolol
Definition
HTN (β1, β2 antagonist)
Term
Labetalol
Definition
HTN (α, β1, β2 antagonist)
Term
Acebutolol
Definition
HTN (β1 antagonist)
Term
Metoprolol
Definition
HTN, CHF (β1 antagonist)
Term
Atenolol
Definition
HTN (β1 antagonist)
Term
Betaxolol
Definition
HTN (β1 antagonist)
Term
Bisoprolol
Definition
HTN, CHF (β1 antagonist)
Term
Esmolol
Definition
HTN (β1 antagonist)
Term
Nebivolol
Definition
HTN (β1 antagonist)
Term
Minoxidil
Definition

HTN (direct vasodilator via inhibition of ATP K channel)

dilates arteries not veins

Term
Diazoxide
Definition
HTN (direct vasodilator via opening of K+ channels)
Term
Fenoldopam
Definition
HTN (direct vasodilator via dopaminergic receptors)
Term
Captopril
Definition
HTN, CHF (ACE inhibitor)
Term
Lisinopril
Definition
HTN (ACE inhibitor)
Term
Enalapril
Definition
HTN, CHF (ACE inhibitor)
Term
Ramipril
Definition
HTN (ACE inhibitor)
Term
Fosinopril
Definition
CHF (ACE inhibitor)
Term
Losartan
Definition
HTN, CHF (ARB)
Term
Valsartan
Definition
HTN (ARB)
Term
Irbesartan
Definition
HTN, CHF (ARB)
Term
Candesartan
Definition
HTN, CHF (ARB)
Term
Telmisartan
Definition
HTN (ARB)
Term
Aliskerin
Definition
HTN (renin inhibitor)
Term
Verapamil
Definition

HTN (phenylalkylamine, Ca2+ channel blocker)

acts on peripheral vasculature and heart

Term
Amlodipine
Definition

HTN (dihydropyridine, Ca2+ channel blocker)

acts on peripheral vasculature

Term
Nifedipine
Definition

HTN (dihydropyridine, Ca2+ channel blocker)

Acts mainly on peripheral vasculature

Term
Nicardipine
Definition

HTN (dihydropyridine, Ca2+ channel blocker)

acts on peripheral vasculature

Term
Nimodipine
Definition

HTN (dihydropyridine, Ca2+ channel blocker)

affects only peripheral vasculature

Term
Diltiazem
Definition

HTN (benzothiazepine, Ca2+ channel blocker)

Has effects in peripheral vaculature and on the heart

Term
Bepridil
Definition
HTN (diarylaminopropylamine, Ca2+ channel blocker)
Term
Bosentan
Definition
HTN, CHF (endothelin receptor blocker)
Term
Digoxin
Definition
CHF (digitalis glycoside)
Term
Hydralazine
Definition
CHF (direct acting vasodilator on arteriolar smooth muscle)
Term
Nitroglycerin
Definition
CHF (nitrosovasodilator)
Term
Nitroprusside
Definition
CHF, HTN (nitrosovasodilator)
Term
Milrinone
Definition
CHF (non-glycoside inotrope)
Term
Dobutamine
Definition

CHF (non-glycoside inotrope)

β1 agonist used in end-stage CHF

Term
α-methyl dopa
Definition
treats severe HTN associated with preeclampsia (false neurotransmitter)
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