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CSULB biol 212 16.4
HOW DO EPIGENETIC CHANGES REGULATE GENE EXPRESSION?
9
Biology
Undergraduate 2
04/22/2011

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Term
What is Epigenetics ?
Definition
Changes in the expression of a gene or set of genes that occur without changing the DNA sequence. Changes are reversible, but sometimes are stable and hereditable.
Term
What two processes are involved in Epigenetics?
Definition

1. DNA Methylation

2. Chromosomal protein alterations

Term
Where does DNA methylation occur?
Definition
Promoters
Term
What is DNA methyltransferase?
Definition
enzyme that catalyzes the addition of a methyl group to the 5`carbon to form 5-methyl cytosine
Term
What are CpG islands?
Definition
DNA regions rich in C and G doublets
Term
What is a maintenance methylase?
Definition
enzyme that catalyzes the formation of 5 methylcytosine in the new DNA strand
Term
What enzyme is involved in catalyzing the removal of the methyl group from cytosine?
Definition
Demethylase
Term
What happens when acetyl groups are added to histones?
Definition
Transcription is activated
Term
Which enzyme is involved in the addition of acetyl groups to histones?
Definition
Histone acetyltransferase
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