Term
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Definition
| Something Known to cause mutations-inherited genotypic changes |
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Term
| Why was the mold Neurospora crassa used in the Beadle and Tatum experiment? |
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Definition
| It is haploid and therefore expresses all alleles phenotypically. It is also simple to culture and grows well in lab. |
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Term
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Definition
| wild type strains that can catalyze all metabolic reactions neede to make all the chemical constituents of their cells |
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Term
| What was used as a mutagen for Neurospora in the Beadle and Tatum experiment? |
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Definition
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Term
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Definition
| unlike prototrophs, auxotrophs need to be supplied with additional nutrients to be able tomake all of the chemical constituents of their cells |
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Term
| What does gene expression contorl? |
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Definition
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Term
What was the name of Garrod's Hypothesis?
(Beadle and Tatum's experiment confirmed this) |
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Definition
| One-gene, one-enzyme hypothesis |
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Term
| Garrod's One-gene, one-enzyme hypothesis was restated as this |
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Definition
| One-gene, one-polypeptide relationship |
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Term
What is the function of a gene?
(in terms of protein synthesis) |
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Definition
| To inform for the production of a single, specific polypeptide |
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Term
| What were the 3 supplements added to the auxotrophic mutant strains in the Beadle and Tatum experiment? |
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Definition
| Ornithine, Citruline, Arginine |
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Term
| Mutant strain 1 was given the 3 supplements but only grew on arginine so it was blocked on which step of making arginine? |
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Definition
| it was blocked on the step going from citruline to arginine-the last step. |
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Term
| Mutant strain 2 was given the 3 supplements but only grew on citruline and arginine so it was blocked on which step of making arginine? |
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Definition
| It was blocked on the step from ornithine to citruline-the second step |
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Term
| Mutant strain 3 was given the 3 supplements and grew on all three so it was blocked on which step of making arginine? |
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Definition
| It was blocked on the step going from the precursor to ornithine-the first step |
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Term
| Essentially what did the results fromthe Beadle and Tatum experiment prove? |
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Definition
| It proved Garrod's one-gene, one-enzyme hypothesis that essentially states that each gene specifies a particular enzyme (later it will be realized that it is not always an enzyme but rather a polypeptide) |
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Term
| What disease did Garrod study and eventually make his one-gene, one-enzyme hypothesis? |
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Definition
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