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CSU BMS 300 Walrond
Human Physiology Unit 5: Endocrine System
36
Physiology
Undergraduate 1
02/15/2013

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Term
What system uses a series of ductless glands to secrete hormones into the blood stream?
Definition
Endocrine system.
Term
What system serves to regulate body functions ranging from calcium metabolism to energy utilization?
Definition
Endocrine system.
Term
What are the two varieties of hormones?
Definition
Protein-based hormones and steroid hormones.
Term
What bind to transmembrane receptors and produce their effects through a cascade of intracellular events?
Definition
Protein hormones.
Term
What are generally lipophilic, cross membranes readily, and bind directly to DNA to effect a response?
Definition
Steroid hormones.
Term
What are often involved in increasing cell division?
Definition
Steroid hormones.
Term
What must cells have to be capable of responding to a given hormone?
Definition
Receptors that are specific for the hormone's function.
Term
What initiates the cascade of events in a cell that ultimately leads to the phosphorylation of proteins?
Definition
The binding of protein hormones to transmembrane protein receptors.
Term
What releases a variety of releasing hormones that regulate the release of hormones from the anterior pituitary?
Definition
Hypothalamus.
Term
Where is the adenohypophysis found?
Definition
Anterior pituitary.
Term
What is an extension of hypothalamic neurons into the pituitary gland? What do these neurons release?
Definition
Posterior pituitary. Vasopressin and oxytocin.
Term
Where is the thyroid gland located?
Definition
Throat.
Term
What is involved with calcium metabolism by releasing calcitonin from the C cells?
Definition
Thyroid gland.
Term
Where is the parathyroid gland located?
Definition
Adjacent to the thyroid gland.
Term
What do the parathyroid glands release? What are they involved in?
Definition
Parathyroid hormone. Involved in calcium metabolism.
Term
Where are the adrenal glands located?
Definition
On top of the kidneys.
Term
What are the tree classes of hormones released from adrenal glands?
Definition
Mineralocorticoids, glucorticoids, and gonadocorticoids.
Term
What controls the release of epinephrine and norepinephrine?
Definition
The sympathetic nervous system.
Term
What are the two main hormones released by the pancreas?
Definition
Glucagon and insulin.
Term
What is the role of glucagon?
Definition
To increase blood glucose levels by releasing stored glucose and by promoting the production of glucose from other sources.
Term
What is the role of insulin?
Definition
It binds to insulin receptors where it activates a tyrosine kinase and leads to the uptake of glucose into the cell.
Term
What maintains hormone levels within a narrow concentration range?
Definition
Negative feedback.
Term
What are the three general mechanisms for the release of hormones?
Definition
Humoral, neural, and hormonal.
Term
What triggers the release of releasing hormones?
Definition
Neurons in the hypothalamus.
Term
Where are releasing hormones released into?
Definition
The blood supply that feeds the anterior pituitary.
Term
What do releasing hormones cause?
Definition
The release of another set of hormones from the anterior pituitary gland.
Term
What is another name for the adenohypophysis?
Definition
Anterior pituitary.
Term
What is another name for the neurohypophysis?
Definition
Posterior pituitary.
Term
What is and extension of the hypothalamus?
Definition
Posterior pituitary.
Term
What hormones does the posterior pituitary release?
Definition
Vasopressin or oxytocin.
Term
What is a peptide hormone that regulates water and salt balance?
Definition
Vasopressin.
Term
What is a peptide hormone that cause smooth muscle contraction in the uterus druing birth or in myoepithelial cells of the mammary glands to eject milk?
Definition
Oxytocin.
Term
How do releasing hormones from the hypothalmic neurons reach the anterior pituitary?
Definition
Through the portal vasculature.
Term
What happens when release hormones arrive in the anterior pituitary?
Definition
They bind to receptors and cause endocrine cells to release hormones which travel in the blood to target glands.
Term
What two places do hormones released from the target gland affect? What is this called?
Definition
Hypothalamus and anterior pituitary. Negative feedback.
Term
Where are cells in the anterior pituitary derived from?
Definition
Embryologically from a outpocketing of epithelial cells in the developing pharynx called Rathke's Pouch.
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