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CSIM 12
Viruses and population level
17
Medical
Undergraduate 2
03/30/2013

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Cards

Term
What are the theories of virus origins?
Definition
1) Regressive evolution
2) Cellular origins
3) Independent entities.
Term
What are the mechanisms of viral evolution?
Definition
1) Mutation
2) Recombination
3) Selection
4) Reassortment
Term
What is the difference between genetic shift and drift and which mechanisms account for each?
Definition
Genetic shift is a major genetic change caused by recombination or reassortment. Genetic drift is the slow accumulation of mutations due to copying errors and immune selection.
Term
Which evolution pathways are favoured by DNA and RNA viruses?
Definition
DNA viruses co-evolve with their host (limited to one species). RNA viruses tend to infect multiple species.
Term
What is a zoonosis?
Definition
A disease and infection which is naturally transmitted between vertebrate animals and humans.
Term
What does sporadic mean?
Definition
Occasional cases occurring at irregular intervals.
Term
What does endemic mean?
Definition
Continuous occurrence at an expected frequency over a certain period of time and in a certain geographical location.
Term
What does epidemic or outbreak mean?
Definition
Occurrence in a community or region of cases of an illness with a frequency clearly in excess of normal expectancy.
Term
What does pandemic mean?
Definition
Epidemic involves several countries or continents affecting a large population.
Term
Where do HIV-1 and HIV-2 come from?
Definition
HIV-1: Chimpanzees
HIV-2: Sooty mangabeys
Term
What kind of virus is SARS?
Definition
A coronavirus.
Term
Where does SARS come from?
Definition
Bats (maybe).
Term
What is H5N1?
Definition
Bird flu.
Term
What is H1N1?
Definition
Swine flu.
Term
What does 'control' mean?
Definition
Reduction of incidence prevalence, morbidity and mortality to a locally accepted level.
Term
What is the difference between elimination and eradication?
Definition
Elimination is a reduction of disease incidence to zero in a certain area. Eradication is worldwide.
Term
What does primary prevention mean?
Definition
Immunisation.
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