Term
| the lung bud becomes the lower respiratory system and is part of the |
|
Definition
| most anterior part of the foregut |
|
|
Term
| The tracheo-esophageal septum, between the lung bud and esophagus, becomes the |
|
Definition
trachealis muscle in the trachea.
Separates digestive from respiratory system. |
|
|
Term
| Malformations associated with incorrect separation of the tracheo-esophageal septum |
|
Definition
Esophageal atresia - blind esophagus
Tracheo-esophageal fistula - aberrant connection between airway and digestive tube |
|
|
Term
| Because mesenchyme produces tenascin and syndecan, epithelial cells know to remain in |
|
Definition
|
|
Term
| Because mesenchyme secretes epimorphin, epithelial cells are |
|
Definition
polarized and know where the lumen/surface ("top") is.
(epimorphin signals location of basal region, "bottom") |
|
|
Term
Branching totals: 27 generations.
Before and after birth? |
|
Definition
23 before birth = 8.3 million alveoli
+4 after birth = 134 million alveoli
(with development of septa = 275 million alveoli) |
|
|
Term
| Secretion of surfactant is during the |
|
Definition
| saccular stage. (week 28) |
|
|
Term
| Every Premature Child Sucks Air |
|
Definition
Embryonic (branch 3x)
Pseudoglandular (branch +14x, terminal bronchioles)
Canalicular (respiratory bronchioles)
Saccular (terminal sacs, type 1/2 alveolar cells, surfactant week 28)
Alveolar (alveoli develop/mature) |
|
|
Term
|
Definition
can be repaired in utero
post natal hernia repair may leave lungs hypoplastic and immature |
|
|
Term
| Critical factor in species selection for models of human pediatric lung |
|
Definition
| timing of alveolar development |
|
|
Term
| % of interstitial tissue in lung decreases with |
|
Definition
|
|
Term
| Massive hemoptysis (coughing up blood) is most likely due to |
|
Definition
|
|
Term
|
Definition
| cannot measure RV, therefore no FRC/TLC |
|
|
Term
| He dilution and N2 washout |
|
Definition
C1V1 = C2V2
For people with obstructive lung disease, these techniques will underestimate the true FRC. |
|
|
Term
| Body Plethysmography can effectively measure FRC even in patients with obstructive lung disease because |
|
Definition
| it uses pressure and volume relationships to measure the entire volume of the lungs including alveolie that may not move gas effectively. |
|
|
Term
| We us ____ to measure the rate of diffusion with a single 10 second breath holding technique. |
|
Definition
|
|
Term
| ERc (Extraction Rate Capacity) is normally |
|
Definition
|
|
Term
| Estimate cardiac output with O2 consumption (CaO2 - CvO2) and minute ventilation. |
|
Definition
CO = VO2 / 10 * (CaO2 - CvO2)
= minute ventilation/10 x O2 consumption |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
