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CP2:8 Respiratory Physiology - Resistance
Questions and stuff
11
Medical
Graduate
01/11/2012

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Term

What is the importance of radius in airway resistance?

R=8nl/πr4

n=viscosity l=length

Definition

If radius is halved

Resistance increases 16x

Term
What is the importance of Reynold's number?
Definition

>2000 means turbulent

directly related to density, velocity, radius

(helium is less dense, more likely to be laminar)

Term
Airway resistance formula
Definition
R = ΔP/flow
Term
Most airway resistance occurs in the
Definition

4-7th division

(4th being the narrowest generation)

This makes small airways disease difficult to detect. 

Term
Closing volumes
Definition
at very low volumes the small airways may close completely
Term

Contraction of the smooth muscles narrow airways.

They can be relaxed using _____.

Definition
β agonists
Term
Parasympathetic activity in the airways causes _____.
Definition
bronchoconstriction
Term
Caliber increases as the lung _____.
Definition
expands
Term
What type of gas is used to improve ventilation in asthmatic?
Definition

heliox

it has lower density than regular O2

Term
In terms of effort, peak expiratory flow is ______ and the slope is ______.
Definition

In terms of effort, peak expiratory flow is effort dependent and the slope is effort independent.

This is due to the choke point.

Term
What is the choke point?
Definition

aka equal pressure point

limits flow

worsened by any increase in airway resistance causing a decrease in the endobronchial pressure (or if the driving force is reduced [emphysema])

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