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Definition
| any disease-producing agent |
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| a lumphocytic cancer associated with infection by Epstein-Barr virus along with a chromosome translocation in which the MYC gene is activated by moving it from chromosome 8 to 14. |
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Definition
| type of lymphoma characterized by the presence of Reed-Sternberg cells, which possess two nuclei and have unique distinctive appearance |
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Definition
| cancer of the epithelial lining of the nasal passages and throat caused by infection with the Epstein-Barr virus; frequent in Southeast Asia but rare elsewhere in the world. |
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Definition
| imflammation of the liver. |
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Definition
| RNA virus that causes hepatitis and liver cancer; transmitted by direct contact with contaminated blood. |
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| HIV (human immunodeficiency virus) |
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Definition
| retrovirus that causes AIDS (acquired immunodeficiency syndrome). |
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Definition
| cancer arising from blood vessels in the skin; generally quite rare, but rates are increased 100-fold in people infected with HIV. |
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| DNA virus derived from monkey cells that causes cancer in animals and that contaminated early batches of polio vaccine. |
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| tiny flatworm that causes inflammation of the blood vessels of the intestine or bladder (achistosomiasis), occasionally leading to bladder cancer. |
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Definition
| transcription factor activated in tissues where inflammation is occurring; activates the transcription of genes that produce proteins that stimulate cell division and make cells resistant to apoptosis. |
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Definition
| condition in which a virus remains "hidden" indise a cell with no new virus particles being produced or released. |
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Definition
| enzyme that uses an RNA template to synthesize a complementary molecule of double-stranded DNA. |
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Definition
| a DNA copy of the genetic information of an RNA virus that has been integrated into the chromosomal DNA of a host cell. |
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Definition
| total genetic information of a virus, cell, or organism. |
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Definition
| any gene whose presence can lead to cancer; some oncogenes are intoduced by viruses, but in humans cancers, most arise by mutation from normal cellular genes called proto-oncogenes. |
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Definition
| normal cellular gene that can be converted into an oncogene by point mutation, gene amplication, chromosomal translocation, local DNA rearrangement, or insertional mutagenesis. |
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| family of protein kinases that catalyze the phosphorylations of the amino acid tyrosine in target proteins; play a predominent role in signaling pathways. |
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Definition
| protein or gene that remains active at all times rather than being regulated by another molecule. |
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Definition
| change in gene activity or structure caused by the chromosomal integration of DNA derived from another source, usually a virus. |
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Definition
| transcription factor that activates the transcription of genes required for cell proliferation. |
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Definition
| oncogene of the avian myelocytomatosis virus; codes for an abnormal version of the Myc transcription factor. |
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Definition
| protein produced by an oncogene present in human papillomavirus (HPV) that binds to and inactivates a cell's normal Rb protein, thereby interfering with the ability of the Rb protein to restrain cell proliferation. |
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