Term
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Definition
| growth of new blood vessels |
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Term
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Definition
| process by which cancer cells stimulate the development of a blood supply. |
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Term
| fibroblast growth factor (FGF) |
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Definition
| signaling protein that stimulates the growth of new blood vessels. |
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Term
| matrix metalloproteinase (MMP) |
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Definition
| family of enzymes that degrade proteins found in the extracellular matrix; referred to as metalloproteinases because they require zinc or calcium atoms to function properly. |
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Term
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Definition
| protein (fragment) that inhibits the growth of blood vessels; a fragment of the protein collagen. |
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Term
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Definition
| formation of microscopic tumor masses that remain dormant for prolonged periods of time. |
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Term
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Definition
| spread of tumor cells from one part of the body to another via the bloodstream or other body fluids. |
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Term
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Definition
| cell-cell adhesion protein that binds epithelial cells to one another. |
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Term
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Definition
| protease that converts plasminogen into plasmin. |
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Term
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Definition
| population of identical cells produced from the reproduction of a single parental cell; also applied to genes or organisms. |
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Term
| major histocompatibility complex (MHC) |
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Definition
| type of cell surface protein recognized by the immune system as part of the process of inducing an immune response. |
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Term
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Definition
| interactions between tumor cells and surrounding normal cells that influence tumor cell proliferation, invasion, and metastasis. |
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Term
| metastasis suppressor gene |
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Definition
| class of genes coding for proteins that inhibit or block events associated with invasion and metastasis. |
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