Shared Flashcard Set

Details

Contraceptives and HRT
Estrogen Progestrogen etc
18
Medical
Professional
04/14/2013

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Cards

Term
Conjugated Equine Estrogen
Definition
Menopausal HRT
Term
17B-Estradiol
Definition
Menopausal HRT
Term
Medroxyprogesterone
Definition
Depo-Contraception an HRT:
(IM INJECTION)--> Bone loss, weight gain, loss fertility ~ 1 yr
Term
Progesterone
Definition
Menopausal HRT

binds weak affinity androgen, estrogen, glucocorticoid receptors

sloughing uterus due to decline p
Term
Ethinyl Estradiol
Definition
Contraceptiong: highest potency estrogen.


increases HDL,Decreases LDL, stimulates stem cell prolif
VASODILATION

Enterohepatic circulation
AVOID CONTRACEPTIVES
Term
Norethindrone
Definition
Synthetic 1st gen progestin contraception
weakest progesterone.

USED AS POP, every day same time,
LACTATING WOMEN = #1 use
Term
Levonorgestrel
Definition
synthetic 2nd gen progestin contraception
MOST POTENT

IUD ALSO (spotting common)reduces lining and increases mucus

HIGH DOSE = ABORTION
Term
Norgestimate
Definition
synthetic 3rd gen progestin contraception
Term
desogestrel
Definition
synthetic 3rd progestin contraception
Term
drosperinone
Definition
synthetic progestin contraception 4gen
(anti-mineralcorticoid/antiandrogen):

reduces NA/H20 retention = less bloating
HYPERKALEMIA!!!

contraindicated kidney disease
INCREASED DVT RISK
Term
How do they stop ovulation
Definition
negitive feedback LH/FSH surge
"recreate leuteal phase"

e = ug
p = mg
Term
two basic types contraception
Definition
1. E+P: Ethynial Estradiol + Lev>Deso>NGM>NE mono = less bleed vs. tri = less exposure

2. progesterone only
higher failure rate and risk bleeding
Term
when to begin contraception
Definition
1st day menstration
1st sunday after menses - back up 1st w
quick start - back up 1st week
Term
missed doses contraception
Definition
1 pill = 2 next
2 pill (week 1/2) = 2 then 2 backup 1
2 pill (week 3) = new pack
a.skip placebos
b. keep taking until sunday
backup 1-week
Term
Benefits/risks COCS
Definition
1. decrease ovarian, endometrial cancer
fibrocystic and fibroadenomas
greater cycle regularity

2. CLOTTING (SMOKER)-- lower risk = lowest e possible
increase BREAST CANCER (4 yrs before 1st preg)

(HYPERTENSION, GALLBLADDER DISEASE, CERVICAL DYSPLASIA)

progestone -> LEVO = worst
impairs glucose tolerance and causes thrombosis
Term
indications progesterone only
Definition
EARLY POSTPARTUM
migraines, smoker
thromboembosism/heart disease
Term
continous E preparations
Definition
long-term exposure E increased
return to fertility takes 3 mo
Term
upristil
Definition
abortion med 5 days out
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