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Constipation
Constipation
28
Pharmacology
Professional
08/27/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Define constipation
Definition

Defined as  infrequent or hard stools, or difficulty assing stools. More specifically, constipation may involved pain during the passage of a bowel movement, the inability to pass a bowel movement after starining or pushing for more than 10 minutes, requiring digital evacuation , or no bowel movements after more than 3 days.

 

Term
Some basic practices to correct constipation
Definition

(1) look for offending drugs

(2) Correct fluid intake (64 ox - caution with CVD)

(3) Limit caffeine & alcohol

(7) Replace refined foods with whole grain products, fruits and vegetables, beans

(8) increase physical activity

(10) Don't delay going to the bathroom when the urge to defacate is present; may need to schedule time.

 

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Term
[image]
Definition
Statement. Not a question.
Term
Describe the use of opioids and constipation
Definition

Prevention: from chronic opiods - regular use of senna (stimulant) plus a stool softener (docusate), alone of in combo products is usually needed and a laxative should be recommended when a scheduled opiod is prescribed.

[image][image][image][image]Wikipedia: Stimulants are psychoactive drugs which induce temporary improvements in either mental or physical function or both.

Term
Morphine and Fentanyl. Which is less constipating?
Definition
Fentanyl is less constipating than Morphine
Term
Is opiod constipation related to dose?
Definition

The higher dose used, the more constipation will be present

Term

Regarding opiods and constipation, what can be used to treat (not prevent) constipation?

Definition
Treatment: lactulose, sorbitol, MOM, mag citrate or Miralax
Term
How to deal with fecal impactaion.
Definition
Enema, may require digital evacuation
Term
Regarding overall constipation, what is first line treatment?
Definition

Bulk laxative

 

Term
brand name for calcium polycarbophil
Definition
FiberCon (bulk laxative)
Term
brand name for psyllium
Definition
Metamucil (bulk laxative)
Term
brand name for methylcellulose
Definition
Citrucel (bulk laxative)
Term
What are emollients & lubricants
Definition
Stool softeners
Term
Name a stool softener
Definition
Docusate Sodium
Term
Brand name for docusate
Definition
Colace
Term
Name stimulants
Definition
Bisacodyl, Senna
Term
brand name for Senna
Definition
Ex - Lax
Term
Name a gut - opiod - R blocker
Definition
Methylnaltrexone
Term
brand name for methylnaltrexone
Definition
Relistor
Term
Name osmotic laxative
Definition

Lactulose, Magnesium salts, sorbitol

 

Term
brand name for Magnesium salts
Definition
MOM
Term

Name a nonabsorbable osmotic

laxative

Definition
Polyethylene glycol
Term
brand name for polyethylene glycol
Definition
Golytely, MiraLax
Term
Is MiraLax tasteless?
Definition
Almost tasteless
Term
Brand name for lubiprostone
Definition
Amitiza
Term
MOA for lubiprostone
Definition

Activates chloride channels in the gut, leading to increased fluid in guy and movement

Term
[image]
Definition
Statement. Not a question.
Term
[image]
Definition
Statement. Not a question.
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