Term
| Connective Tissue is derived from what embryonic germ layer? |
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Definition
| Mesoderm and Head region CT is derived from the Neural crest (Ectoderm). |
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Term
| What are some of the functions of Connective Tissue? |
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Definition
> Maintains form and structure > Fills Spaces > Supports Soft Tissue > Stores Fat > Mechanical Role > Defense - phagocytic cells and immune cells. > Forms physical barrier |
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Term
| What 2 amino acids are unique to Collagen? |
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Definition
| Hydroxyproline and Hydroxylysine |
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Term
| Every third Amino Acid in a collagen chain is ______? |
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Definition
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Term
| What is the structure of Collagen? |
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Definition
| Collagen is composed of 3 alpha chains of polypeptides. The three chains coil into a triple helix. |
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Term
| where are the alpha polypetide chains synthesized? |
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Definition
| In the Rough Endoplasmic Reticulum. |
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Term
| Which enzyme catalyzes formation of covalent crosslinks in fibril formation? |
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Definition
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Term
| What are the four most important types of collagen and where are they found? |
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Definition
Type I is found in skin and bone Type II is found in cartilage Type III is found in blood vessels Type V is found in ______ |
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Term
| WHat are some unique characteristics of Elastic Fiber? |
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Definition
| They contain 2 unique amino acids, called demosine and isodesmosine. It is made of elastin surrounded by microfibrils made of fibrillin. |
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Term
| What are some differeniating features of Reticular fibers? |
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Definition
| They are comprised of Type III collagen that is heavily glycosylated. |
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Term
| What are some of the functions of ground substances. |
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Definition
| They function to fill spaces, act as a lubricant, a very viscous barrier and they bind cells to fibers. |
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Term
| Which GAG does not form proteoglycans? |
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Definition
| Hyaluronic Acid, because it is not sulfated. |
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Term
| WHat are the 5 types of GAG's |
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Definition
| Hyaluronic Acid, Heparan sulfate, Keratan sulfate, Chondroitin Sulfate, Dematan Sulfate |
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Term
| What is the composition of a GAG? |
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Definition
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Term
| WHat is the function of the mast cells in the CT? |
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Definition
| The mast cells contain two types of granules, the heparin and histamine. When the IgE antibody binds to a surface recpetor, these granules are released and causes local inflammation. (Allergic reaction) |
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Term
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Definition
| The release of granule contents by the mast cell as an allergic reaction. |
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