Shared Flashcard Set

Details

Complementary and Alternative Medicine
Dr. K.
12
Medical
Professional
12/16/2012

Additional Medical Flashcards

 


 

Cards

Term
What is derived from the foxglove leaf?
Definition
Digitalis and digitoxin. Used in CHF an dinhibits Na/K ATPase
Term
what drug is derived from the vinca periwinkle plant and what does it treat? MOA?
Definition
vinblastine and vincristine. treats a varity of leukemias by inhibiting microtubule formation and mitosis
Term
Ginko Biloba
Definition
extracts are flavonoids. They are anti-inflammatory, antioxidant, radical scavengers, and inhibit platelet aggregation.
Indicated in Alzheimers, vascular dementia, claudication, and tinnitus.
Bleeding can occur if used w/ warfarin
Term
Saw Palmetto
Definition
used in benign prostatic hypertension
inhibits 5-a-reductase, DHT binding to receptors, prostaglanding synthesis, and antagonizes a-1 receptors on prostatic capsule.
Gives false negative elevated PSA and interferes w/ iron absorption.
Term
Black Cohosh
Definition
used for treatment of menopausal symptoms (sleep/mood disturbances and hot flashes)
estrogen receptor mediated effect.
Avoid in breast cancer pts. Hepatotoxicity risk.
SEs - GI distress, N/V.
Term
St Johns Wart
Definition
treatment of mild to moderate depression, anxiety, or sleep disorders.
active agents are hyperforin, and hypercin.
inhibits MOA. Inhibits serotonin, dopamine, and NE reuptake. increase binding affinity for serotonin, benzodiazepine and muscarinic receptors.
Induces cP450. inactive OCP, simvastatin, PIs, and warfarin.
Contraindicated in antidepressants (esp SSRIs)
Term
Echinachea
Definition
used for infectious disease symptom treatment.
Alkamide possesses anti-inflammatory COX1 and 2 effects.
SEs - allergic rxns, muscarinic inhibition, exacerbation of immune diseases (MG), inhibit cP450, and GI hemorrhage w/ NSAIDs
Term
Ginseng
Definition
activation of monocytes. Stimulate TNF, IFN-y, and IL-2.
Improved vitality, immunity, cognition, and libido.
Restores homeostasis
SEs - insomnia, diarrhea, vaginal bleeding. Contraindicated in schizo. Inhibit platelets. increase QT. hypoglycemic effects.
Term
Kava
Definition
intoxicating, sedative, local anesthetic, tranquilizing, anti-inflammatory, anti-microbial, anti-cancer. Potentiate GABA.
can cause serious hepatotoxicity, exacerbate parkinsons and cause kava dermopathy (psoriasis). w/ alcohol increases depressant effect.
Term
Noni
Definition
inhibit superoxide radical formation
Anti-tumor effects
anti-inflammatory
weight loss promotion
Term
Glucosamine
Definition
seashell extract of amino-monosaccharides
A substrate for glycosominoglycan and proteoglycan synthesis.
Selective uptake by cartilage.
Inhibits proinflammatory cytokines, PGE, phagocytosis and lysozyme release
Term
Garlic
Definition
inhibit cholesterol synthesis, reduce blood pressure, inhibit platelet aggregation. Antimicrobial properties.
SEs - potentiates anti-coagulants, nausea, GI irratation
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