Shared Flashcard Set

Details

Complement
Complement and receptors
21
Medical
Graduate
10/26/2010

Additional Medical Flashcards

 


 

Cards

Term
Cell Lysis
Definition
C5b678(9n) or C5b678
Term
Opsonization
Definition
C3b, C4b (iC3b, iC4b)
Term
Solubilization/Clearance
Definition
C3b (iC3b)
Term
Chemotaxis
Definition
C5a >> C5b67
Term
Mast cell Degranulation
Definition
C5a > C3a, C4a = anaphylatoxins
Term
B cell co-acticvation
Definition
C3d
Term
Opsonic and adhesion receptors
Definition
CR3, CR4 > CR1
Term
Anaphylaxis receptor
Definition
C5aR > C3a/4aR Mast cell, basophils, smooth muscle
Term
Chemotactic receptors
Definition
C5aR neutrophils
Term
Clearance receptor (soluble)
Definition
CR1
Term
B cell co-receptor
Definition
CR2 complex
Term
Internal thioester bond
Definition
Stabilization of C3b and C4b by binding things with an amino group (antigen surface proteins)
Term
C4bBP
Definition
Binds to and inhibits C4b joining C2a and forming a C3 convertase
Term
S protein
Definition
Binds C5b67 and prevents it from binding C8 and ultimately the MAC complex
Term
Factor P
Definition
Stabilizes C3 convertase forming C3bBbP
Term
CR1
Definition
Complement receptor that block C3 convertase formation
Term
DAF
Definition
Decay accelerating factor; induces C3 convertase decay
Term
Factor H
Definition
Binds to C3b preventing C3bBb formation
Term
Factor I
Definition
Cleaves and inactivates C3b and C4b generating iC3b and iC4b
Term
Anaphylatoxin inhibitor
Definition
Cleaves and inactivates C3a, C4a, and 5a
Term
4 methods of regulation
Definition
blocking
proteolysis
stabilization
dissociation
Supporting users have an ad free experience!