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Complement Inhibitors
n/a
9
Immunology
Graduate
01/21/2011

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Cards

Term
C1-Inhibitor
Definition
Binds to C1r,C1s, removes it from C1q, cofactor for I
Term
C4-Binding Protein
Definition
Binds to C4b removing C2b, co-factor for C4b cleavage by Factor I
Term
CR1
Definition
Binds C4b, removes C2b, Binds C3b, removes Bb
Term
Factor H
Definition
Binds to C3b removes Bb; cofactor for I
Term
Delay Accelerating Factor
Definition
displaces Bb from C3b and C3b from C4b
Term
Membrane Cofactor Protein
Definition
promots C3b and C4b inactivation by I
Term
CD59
Definition
prevents MAC formation
Term
S Protein
Definition
binds C5-7, prevents insertion into membrane
Term
Clusterin
Definition
binds C5-7, prevents insertion into membrane
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