Term
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Definition
Includes:
-Prothrombin (F2)
-Factor 7
-Factor 9
-Factor 10
Produced in the liver
Dependent on vitamin K |
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Term
|
Definition
Includes:
-Fibrinogen
-Factor 5
-Factor 8
-Factor 13
Activated by thrombin during coagulation
F5 and F8 are co-factors that aid in activation |
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Term
|
Definition
Includes:
-Factor 11
-Factor 12
-Prekallikrin (PK)
-High Molecular Weight Kininogen (HMWK or HK) |
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Term
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Definition
| 3 pathways: Intrinsic, Extrinsic, Common |
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Term
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Definition
Consists of enzymes and proteins in the plasma
Tested for using the PTT Test
Starts with F7
-F7 is activated by HWMK to become F7a
-F7a activates F11
-F11 activates F9 |
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Term
| Intrinsic Pathway Factors |
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Definition
F12
PK
HK
F11
F9
F8
Von-Willebrand's Factor |
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Term
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Definition
Enzymes, co-factors, activators, and tissue factors found in the plasma
Tested for by using the prothrombin test (PT)
Occurs when tissue factor acts on F7
-F7 activates F9 |
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Term
| Extrinsic Pathway Factors |
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Definition
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Term
|
Definition
The intrinsic and extrinsic pathways come together to form fibrin
F9 activates F10
-F10 activates prothrombin to become thrombin
-Thrombin activates fibrinogen to become fibrin |
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Term
|
Definition
F10
F5
Prothrombin
Fibrinogen
F13 |
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