Term
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Definition
secreted by endothelial cells to prevent the formation of platelet plugs and Fibrin Clots
Counteracts constriction by causing vasodilation
inc. bloodflow to area
inhibits activation of platelets
inhibits aggregation of platelets at lower concentration than is necessary to prevent |
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Term
| First response to vessel injury is... |
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Definition
| constriction of the lumen |
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Term
| required for vascular integrity |
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Definition
a. Functional thrombocytes
b. adequate connective tissue such as collagen and hyaluronic acid |
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Definition
| product of platelet activation |
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Definition
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Definition
| Produced by endothelial cells |
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Term
| regulatory milecules that interact with receptors on the surface of cells of blood vessel walls |
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Definition
Serotonin
Thromboxane A2
Endothelin
Plasminogen activators
Fibronectin |
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Term
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Definition
| Secreted by endothelium; leads to production of plasmin ans degradation of any thrombi that do form |
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Term
Prostoglandins
(PGI2, Prostocyclin) |
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Definition
| synthesisized and secreted by endothelial cells |
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Definition
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Definition
| On Luminal surface; interacts with and potentiates Antithrombin III (A natural circulating anticoagulant),to prevent formation of thrombi. |
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Definition
| Secreted onto endothelial cell membrane where it activates Protein C & Degrades factors V and VIII |
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Definition
| Synthesized and secreted by endothelial cells; is vasodilator, inhibits activation of platelets, prevents formation of clots w/i blood vessels |
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Term
| tPA (tissue plasminogen inhibitor) |
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Definition
| PAI-I (plasminogen activator inhibitor) synthesized by endothelial cells are involved in control of fibrinolysis |
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Term
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Definition
| receptor for fibrinogen; also binds fibronectin and vonWillebrand factor |
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