Term
| IN THE COAGULATION CASCADE THROMBIN ACTIVATE WHAT 3 MAIN THINGS? |
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Definition
| PLTS, FIBRINOGEN TO FIBRIN, AND FACTORS 13,5,8,4(CALCIUM) |
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Term
| WHAT LIMITS COAGULATION BY LIMITING THE AMOUNT OF TIME PLTS SPEND NEAR THE DAMAGED SITE? |
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Definition
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Term
| WHAT 4 MECHANISMS PLAY A REGULATORY ROLE IN COAGULATION? |
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Definition
| FIBRINOLYSIS, TISSUE FACTOR PATHWAY INHIBITOR (TFPI) WHICH INHIBITS 1ST STEP OF EXTRINSIC PATHWAY, PROTEIN C SYSTEM, AND SERINE PROTEASE INHIBITORS. |
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Term
| DURING FIBRINOLYSIS WHAT IS ACTIVED BY TPA FROM THE VASCULAR ENDOTHELIUM? |
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Definition
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Term
| WHAT IS ACTIVATED PLASMINOGEN CALLED? |
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Definition
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Term
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Definition
| DEGRADES FIBRIN AND FIBRINOGEN, INHIBITS COFACTORS V AND VIII, AND REDUCES PLT GLYCOPROTEIN SURFACE RECEPTORS |
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Term
| DOES PLASMIN CIRCULATE EVERYWHERE? |
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Definition
| NO (WOULD LEAD TO DIFFUSE BLEEDING). PLASMIN IS A LOCAL OCCURENCE. |
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Term
| WHAT DOES TISSUE FACTOR PATHWAY INHIBITOR DO? |
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Definition
| INHIBITS THE TISSUE FACTOR/FACTOR VIIA COMPLEX. THIS IS THE FIRST STEP OF THE EXTRINSIC PATHWAY. |
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Term
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Definition
| IT INHIBITS THROMBIN AND COFACTOR VA AND VIIIA. |
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Term
| PROTEIN C IS ACTIVATED BY WHAT? |
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Definition
| THROMBOMODULIN (WHICH BINDS TO AND REMOVES THROMBIN) |
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Term
| WHAT PROTEIN DOES PROTEIN C COMBINE WITH? |
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Definition
| PROTEIN S. BOTH PROTEIN C AND PROTEIN S ARE VITAMIN K DEPENDENT FACTORS |
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Term
| SERINE PROTEASE INHIBITOS THINK WHAT? |
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Definition
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Term
| WHAT 2 FACTORS ARE ASSOCIATED WITH ANTITHROMBIN? |
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Definition
| ANTITHROMBIN (ANTITHROMBIN III) AND HEPARIN COFACTOR II |
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Term
| WHAT DOES ANTITHROMBIN BIND TO AND INHIBIT? |
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Definition
| THROMBIN (IIA), IXA, XA, XIA, AND XIIA. |
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Term
| ACQUIRED ANTITHROMBIN DEFICIENCY (MORE CLOTS) OCCURS IN WHAT 8 DISEASES/STATES? |
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Definition
| LIVER DISEASE, PROLONGED HEPARIN ADMINISTRATION, NEPHROTIC SYNDROME, DIC, SEPSIS, PREECLAMPSIA, ORAL CONTRACEPTIVE USE, AND DURING CARDIOPULMONARY BYPASS |
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Term
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Definition
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Term
| WHAT DRUG ACCELERAT ANTITHROMBIN ACTIVITY? |
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Definition
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Term
| GP-IB IS IN PLTS AND WHAT BINDS TO THAT? |
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Definition
| VWF WHICH INITIATION OF PLT CROSS BRIDGING. |
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Term
| GP-IIB/IIIA IS IN PLTS AND WHAT BINDS TO THAT? |
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Definition
| FIBRINOGEN TO FORM THE PLT PLUG |
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