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Coagulation Cascade
Hemostasis
13
Medical
Undergraduate 2
03/21/2012

Additional Medical Flashcards

 


 

Cards

Term
Primary Hemostasis Involves...
Definition

adhesion

 

activation

 

aggregation

 

contraction

Term
Secondary Hemostasis Steps
Definition

tissue factor acts with platelet factors

 

thrombin is produced

 

thrombin converts to fibrinogen

 

fibrin deposists at site of injury

Term
Tertiary Hemostasis
Definition

regulatory proteins keep coagulation cascade at site of injury

 

coagulation cascade ceases

 

clot is dissolved through proteolysis

Term
Hemostatic Bleeding
Definition
inability to form a platelet plug
Term
Hemostatic Thrombosis
Definition
inability to regulate the hemostatic system
Term
Localized Bleeding
Definition

important to determine cause of hemorrhage

 

trauma or acute injury

Term
General Bleeding
Definition

important to determine cause of hemorrhage

 

underlying defect in the primary or secondary hemostatic system 

Term
Mucocuteaneous Bleeding
Definition
primary hemostatic defect
Term
Anatomic Bleeding
Definition
secondary hemostatic defect
Term
Tertiary Hemostasis
Definition
chemical events that stop clot formation and dissolve clot once vascular integrity has been restored
Term
Laboratory Assay - Prothrombin Time
Definition

aka PT

 

measured in seconds

Term
Laboratory Assay - Partial Thromboplastin Time
Definition

aka APTT

 

measured in seconds

Term
Laboratory Assay - Thrombin Time
Definition
measured in seconds
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