Term
| What stain is used for astrocytic tumors? |
|
Definition
|
|
Term
| How do you detect a melanoma in the CNS? |
|
Definition
| you will see black melanin stains |
|
|
Term
| what is MIB-1 marker used for? |
|
Definition
| shows aggression of tumor |
|
|
Term
| What is the chromosomal defect if glioblastomas? |
|
Definition
|
|
Term
| What is the treatment used for glioblastomas and what does it target? |
|
Definition
| monoclonal antibody to EGFR gene |
|
|
Term
| what is the chromosomal abnormality in NF-2? what tumors develop? |
|
Definition
chromosome 22
ependymoma, meningioma, schwannoma |
|
|
Term
| what is the chromosomal abnormality in medulloblastoma? |
|
Definition
|
|
Term
| where are neurofibrillary tangles found |
|
Definition
Progressive supranuclear palsy
Post-encephalitic Parkinson's
ALS
Alzheimer's disease |
|
|
Term
| Where is granulovacuolaor degeneration found? |
|
Definition
Pyramidal neurons
normal aging
Pick's |
|
|
Term
| Where are Hirano bodies found |
|
Definition
normal aging
Parkinson's
ALS of guam |
|
|
Term
|
Definition
4q = alpha synuclein
Parkinson's |
|
|
Term
| loss of neurons and neuromelanin pigment with accumulation in macrophages |
|
Definition
|
|
Term
10-25% of dementias
second to alzheimer's disease |
|
Definition
| Diffuse Lewy Body Disease |
|
|
Term
Minimal Parkinsonism
Hallucinations
No cortical tangles |
|
Definition
| Alzheimer's disease, Lewy body variant |
|
|
Term
axial rigidity
supranuclear gaze palsy
male |
|
Definition
| Progressive supranuclear palsy |
|
|
Term
50-100 gram or more loss of cortex
Lacunar infarcts |
|
Definition
|
|
Term
Subacute arteriosclerotic encephalopathy
etat crible
recurrent, brief neurologic deficits |
|
Definition
|
|
Term
Decrease in social function and personality
Hyperorality
Frontal temporal atrophy |
|
Definition
|
|
Term
chromsome 4p
atrophy of str |
|
Definition
|
|
Term
Chromosome 4p
Atrophy of striaum
Neuronal loss and gliosis |
|
Definition
|
|
Term
Muscle weakness in distal extremities that progress
Bunina bodies
Shrunken anterior nerve roots |
|
Definition
| Amyotrophic Lateral Sclerosis |
|
|
Term
| Plaques made of alternating, concentric rings of demyelinated and myelinated white matter |
|
Definition
|
|
Term
Sudden headache, vomiting, fever
Scattered foci of yellow/grey discoloration around the blood vessel |
|
Definition
| Acute disseminated encephalomyelitis |
|
|
Term
|
Definition
|
|
Term
Perivascular infiltrates of lymphocytes, macrophages, and plasma cells
Loss of myelin |
|
Definition
| Acute disseminated encephalitis |
|
|
Term
Soft, swollen brain
Hemorrhage of cerebrum, cerebellum, and pons
Fibrinoid necrosis of small blood vessels |
|
Definition
| Acute Hemorrhage Leukoencephalopathy |
|
|
Term
Involves basis pontis
Due to rapid correction of hyponatremia
preservation of axons
Fusiform region of grey discoloration in basis pontis |
|
Definition
| Central Pontine Myelinolysis |
|
|
Term
Malnourished Italian male
Convulsions, Coma
Decreased oligodendrocytes
hyaline thickening of bc |
|
Definition
| Marchiava-Bignami Disease |
|
|
Term
| Non-indicators for muscle biopsy |
|
Definition
Myasthenia gravis
Myotonias
Rhabdomyolysis |
|
|
Term
| Gomori's trichome stain for sarcoplasma and mitochondria |
|
Definition
sarcoplasma: green
mitochondria: red |
|
|
Term
|
Definition
|
|
Term
Stain for intermyofibrillary network
Stain for denervation/reinnervation |
|
Definition
| NADH-Tetrazolium Reductase |
|
|
Term
|
Definition
|
|
Term
Denervated fibers dark
Degenerating fibers dark
Lymphocytes and macrophages dark |
|
Definition
|
|
Term
good connective tissue stain
myofibers stain red
endo and perimysium blue |
|
Definition
|
|
