Term
|
Definition
| inflammation of the lining surrounding the brain and spinal cord |
|
|
Term
|
Definition
skin and mucous membranes
blood and lymph
blood/brain barrier |
|
|
Term
| microbial strategies to bypass defenses |
|
Definition
IgA protease
antiphagocytic capsules |
|
|
Term
|
Definition
|
|
Term
| bacterial men. causative agents |
|
Definition
strep pneumoniae
neisseria meningitidis
hemophilis influenzae |
|
|
Term
|
Definition
|
|
Term
| bacterial men. transmission |
|
Definition
|
|
Term
|
Definition
early: sore throat, fever, headache, stiff neck, drowsiness, nausea/vomiting
late: coma, neurological disorders, death |
|
|
Term
| strep. pneumoniae etiology |
|
Definition
Gm + cocci
antiphagocytic capsule
IgA protease
mortality: 30-40%
complications: seizures, deafness, blindness |
|
|
Term
| neisseria meningitidis etiology |
|
Definition
Gm - diplococci
antiphagocytic capsule
IgA protease
commonly carried asymptomatic
mortality: 100% untreated, 5-10% treated
complicaitons: rash, no permanent CNS damage |
|
|
Term
| hemophilus influenzae type b etiology |
|
Definition
Gm - rod
antiphagocytic capsule
IgA protease
kids
mortality: 6%
complications: deafness, retardation, seizures |
|
|
Term
|
Definition
entry: nasopharynx-->blood-->CSF
attach: mucosa of nasopharyns
avoid: protected environment, IgA protease
damage: initial: mucosa damage to get into bllod stream
late: inflammation, CNS swelling, capillary damage
exit: coughing sneezing |
|
|
Term
|
Definition
spinal tap to remove CSF
microscopy
Gm staining
ELISA testing
culture |
|
|
Term
|
Definition
|
|
Term
| men. strep. pneumoniae treat |
|
Definition
| vaccine - pneumovax 23-valent |
|
|
Term
| men. neisseria meningitidis treatment |
|
Definition
vaccine
prophylatic rifampicin |
|
|
Term
| men. hemophilus influenzae treatment |
|
Definition
|
|
Term
|
Definition
acute viral infection affecting the CNS of animals
lethal |
|
|
Term
|
Definition
Rhabdovirus
ssRNA negative
bullet shaped capsid
enveloped |
|
|
Term
|
Definition
|
|
Term
|
Definition
primarily parenteral route
usually animal bite
saliva from infected animal needs to get under skin |
|
|
Term
| rabies clinical signs and symptoms |
|
Definition
| low grade fever, pain, numbness, tingling, anxiety, stress, tension, restlessness, excitability, drooling, foaming at mouth, loss of muscle control, muscle spasms, convulsions, brain lesions, death |
|
|
Term
|
Definition
entry: parenteral route
attach: connective tissue
avoid: intracellular the protected environment
damage: behavioral changes, paralysis of swallowing reflex
exit: replicates and released through salvia |
|
|
Term
|
Definition
| post mortem examination of brain tissue |
|
|
Term
|
Definition
| post exposure vaccination |
|
|
Term
|
Definition
| vaccination of domestic pets and bat researchers, spelunkers, and wild-life personnel |
|
|
