| Term 
 
        | Analgesics: NSAIDs mild to moderate pain
 |  | Definition 
 
        | Celebrex Advil
 Toradol- IV, IM
 GI Upset
 |  | 
        |  | 
        
        | Term 
 
        | Analgesics: Non-Opioids mild to moderate pain
 |  | Definition 
 
        | Tylenol Aspirin
 GI Upset, Gastric/esoph bld
 Adverse: Ototoxic & Hepatotoxic
 |  | 
        |  | 
        
        | Term 
 
        | Analygesics: Opioids Moderate to severe pain
 |  | Definition 
 
        | Morphine Sulfate (Duramorph) Meperidine (Demerol)
 const, ↓RR, drowsy
 W/drawal
 |  | 
        |  | 
        
        | Term 
 
        | Analygesics: Opioid Antagonists Immed onset, ½ life 60-90 min
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Barbiturates Anti-Convulsant Agents
 |  | Definition 
 
        | Phenobarbital cerebral cortex
 ↓HR, ↓ RR, ↓ BP, drowsy
 |  | 
        |  | 
        
        | Term 
 
        | Benzodiazepines Anti-Convulsant Agents
 |  | Definition 
 
        | Clonazepam (Klonopin) nerve cells
 ↓HR, ↓ RR, ↓ BP, drowsy
 |  | 
        |  | 
        
        | Term 
 
        | Succinimides Anti-Convulsant Agents
 |  | Definition 
 
        | Ethosuxzimide nerve cells
 ↓HR, ↓ RR, ↓ BP, drowsy, pink urine
 |  | 
        |  | 
        
        | Term 
 
        | Miscellaneous Anti-Convulsant Agents
 |  | Definition 
 
        | Valporic Acid (Depakote) nerve cells,↓Na,↓GABA
 ↓HR, ↓ RR, ↓ BP, drowsy
 SIADH, tinnitus
 |  | 
        |  | 
        
        | Term 
 
        | Hydantoins Anti-Convulsant Agents
 |  | Definition 
 
        | Phenytoin (Dilantin) motor cortex
 ↓HR, ↓ RR, ↓ BP, drowsy, gingival hyperplasia
 |  | 
        |  | 
        
        | Term 
 
        | Iminostilbenes Anti-Convulsant Agents
 |  | Definition 
 
        | Tegretol motor cortex
 ↓HR, ↓ RR, ↓ BP, drowsy
 |  | 
        |  | 
        
        | Term 
 
        | Skeletal Muscle Relaxants ↓spasms neuromuscular junc; ↓spasticity after spinal cord injuries, strokes, CP, or MS
 |  | Definition 
 
        | Soma Flexeril
 Valium
 Dizzy, drowsy, disoriented
 Monitor for severe weakness or numbness in extremities; lg doses may lead to dependency
 |  | 
        |  | 
        
        | Term 
 
        | Neuromuscular Blocking Agents ↓ACH neuromuscular junc; block nerve impulse trans to cause paralysis
 |  | Definition 
 
        | Norcuron Dizzy, drowsy, disoriented
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | blurred vision, dry mouth, constipation, urinary retention |  | 
        |  | 
        
        | Term 
 
        | Adverse Effects (Extrapyramidal) Anti-Psychotic Agents
 |  | Definition 
 
        | Akathisia (need to move) Dystonia (twisting/repetitive movemt)
 Drug-induced Parkinsonism
 Neuroleptic Malignant Syndrome (unstable BP, ↑T, sweating)
 |  | 
        |  | 
        
        | Term 
 
        | Antipsychotic: Phenothiazines Block dopamine receptors
 |  | Definition 
 
        | Thorazine Haldol
 Anticholinergic effects, extrapyramidal adverse effects, monitor WBC
 |  | 
        |  | 
        
        | Term 
 
        | Antipsychotic:Atypical Agents Block dopamine receptors
 |  | Definition 
 
        | Risperdal Zyprexa
 Anticholinergic effects, extrapyramidal adverse effects, monitor WBC
 |  | 
        |  | 
        
        | Term 
 
        | Anti-Depressant Agents: Serotonin-Selective Reuptake Inhibitors (SSRIs)Also used to treat OCD, anxiety disorders, panic disorders, PTSD; ↑NE/serotonin |  | Definition 
 
        | Prozac Zoloft
 Paxil
 Cymbalta
 insomnia, nervousness, takes several wks
 |  | 
        |  | 
        
        | Term 
 
        | Anti-Depressant Agents:Tricyclic Antidepressants (TCAs) ↑NE/serotonin
 |  | Definition 
 
        | Amitriptyline (Elavil) drowsy, dizzy, ↓BP, ↑wt, sex dys,  anticholinergic SE; takes several wks
 |  | 
        |  | 
        
        | Term 
 
        | Anti-Depressant Agents: Monoamine Oxidase Inhibitors (MAOIs) Inhibit MAO to ↑NE
 |  | Definition 
 
        | Nardil drowsy, dizzy, ↓BP,↑wt, sex dys,  anticholinergic SE; takes several wks; Interacts w/ tyramine (red wines, aged cheese, liver, fava beans, yogurt, choc)
 |  | 
        |  | 
        
        | Term 
 
        | Antacids Neutralize gastric acid (>pH)
 (↑ pH from 1.3 to 3.0)
 |  | Definition 
 
        | MOM, TUMS, Maalox, Mylanta D/C LT use; Shake well; w/ 6-8 oz of water
 Interacts w/ ALL PO meds & EC Tabs; sep other meds by 1-2 hr
 |  | 
        |  | 
        
        | Term 
 
        | Proton Pump Inhibitors Blocks action of H+/K+ pump in parietal cells of stomach
 |  | Definition 
 
        | Omeprazole Lansoprazole
 Pantoprazole
 Esomeprazole
 N/V, abd cr; Tabs whole (do not chew)
 Interacts w/ ALL PO meds & EC Tabs; sep other meds by 1-2 hr
 |  | 
        |  | 
        
        | Term 
 
        | H2 Receptor Antagonists Block histamine to ↓acid secretion
 |  | Definition 
 
        | Famotidine Ranitidine
 N/V, abd cramp; h/a, dizzy, loss of libido
 Interacts w/ ALL PO meds & EC Tabs; sep other meds by 1-2 hr
 |  | 
        |  | 
        
        | Term 
 
        | Cytoprotective Agents Stimulate mucus production in GI Tract
 |  | Definition 
 
        | Carafate Cytotec
 N/V, abd cramp; Prostaglandin Effect;
 CI pregnancy
 Interacts w/ ALL PO meds & EC Tabs
 |  | 
        |  | 
        
        | Term 
 
        | Adsorbents Treat Acute Poisoning
 |  | Definition 
 
        | Activated Charcoal Black stools; w/in 30 min
 |  | 
        |  | 
        
        | Term 
 
        | Antidiarrheal: Opioids ↓ or inhibit peristalsis
 ↓stool volume, ↑viscosity, ↓fl/electro loss
 |  | Definition 
 
        | Immodium A-D drowsy, constipation, ↓RR; Interacts w/ CNS depressants; Avoid dairy; bland diet; Call MD if D> 2 days
 |  | 
        |  | 
        
        | Term 
 
        | Antidiarrheal:Adsorbents Bind to bacteria in GI tract & cause soothing effect
 ↓stool volume, ↑viscosity, ↓fl/electro loss
 |  | Definition 
 
        | Pepto-Bismol Avoid dairy; bland diet; Call MD if D> 2 days
 |  | 
        |  | 
        
        | Term 
 
        | Laxative: Bulk-Forming ↑stool mass & water content to promote peristalsis
 |  | Definition 
 
        | Metamucil N/V/D, abd cr; Monitor chronic use; sense abd fullness, intes/esoph obstr; w/ 8 oz water
 |  | 
        |  | 
        
        | Term 
 
        | Laxative: Hyperosmotic Draw water into intestine (hyperosmosis); distention from fl accum promotes peristalsis & BM
 |  | Definition 
 
        | Miralax N/V/D, abd cr; Monitor chronic use
 Fl & electro imbalances
 |  | 
        |  | 
        
        | Term 
 
        | Laxative: Stool Softener Form emulsion btwn fat & water to penetrate stool
 |  | Definition 
 
        | Colace N/V/D, abd cr; Monitor chronic use; in milk or fruit juice to mask bitter taste
 |  | 
        |  | 
        
        | Term 
 
        | Laxative: Lubricants Lubricates feces
 |  | Definition 
 
        | Mineral Oil N/V/D, abd cr, Monitor chronic use
 |  | 
        |  | 
        
        | Term 
 
        | Laxative: Stimulant Stimulate peristalsis
 |  | Definition 
 
        | Dulcolax Correctol
 N/V/D, abd cr; Monitor chronic use
 |  | 
        |  | 
        
        | Term 
 
        | Antiemetic: Phenothiazine Block dopaminergic receptors in CTZ in brain – for active vomiting
 |  | Definition 
 
        | Prochlorperazine (Compazine) Promethazine (Phenergan)–IV, IM, PR, phlebitis; insomnia, h/a, dizzy, Sensory/perceptual alterations
 |  | 
        |  | 
        
        | Term 
 
        | Antiemetics: Serotonin Receptor Antagonist Block Serotonin stimulation
 |  | Definition 
 
        | Zofran insomnia, h/a, dizzy,
 Sensory/perceptual alterations
 |  | 
        |  | 
        
        | Term 
 
        | Antiemetics: Anticholinergic Block ACH release
 |  | Definition 
 
        | Scopolamine insomnia, h/a, dizzy,
 Sensory/perceptual alterations; applied behind ear (at least 4-5 hrs b/f antiemetic effect required)
 |  | 
        |  | 
        
        | Term 
 
        | Digestive Agents Treat deficiencies of pancreatic exocrine secretion
 Assist with digestion of proteins, carbohydrates, and fats
 |  | Definition 
 
        | Pancreatin Pancrelipase
 N/V/adm cr; Admin b/f, w/,after meal
 |  | 
        |  | 
        
        | Term 
 
        | Oral Electrolyte Mixtures Mild to moderate fluid losses
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Nutritional Supplements-Enteral: PO, GT, NGT-Directly to stomach |  | Definition 
 
        | Ensure Ensure Plus
 Diarrhea
 |  | 
        |  | 
        
        | Term 
 
        | Nutritional Supplements-Parenteral: IV Proteins (amino acids), fats, glucose, electrolytes, minerals, vitamins
 |  | Definition 
 
        | Total Parenteral Nutrition (TPN) Intralipids (IL)
 Phlebitis, Fl overload, Hyperglycemia
 |  | 
        |  | 
        
        | Term 
 
        | Fat Soluble Vit A, D, E treat/prevent deficiencies
 K synthesize clotting factors
 |  | Definition 
 
        | A: Retinol D: Cholecalciferol (Calcification)
 E: Tocopherol
 K: dizzy, chest pain, rash, flushing
 |  | 
        |  | 
        
        | Term 
 
        | B1: Thiamine B2: Riboflavin
 B3: Niacin
 B6: Pyridoxine
 C: Ascorbic Acid
 |  | Definition 
 
        | Allergic reactions w/ IV admin Check liver function, blood glucose levels, & serum uric acid levels
 |  | 
        |  | 
        
        | Term 
 
        | Trace Minerals Supplement nutritional def
 |  | Definition 
 
        | Ca, Zinc, Mg (bones/teeth) Phos, Fluoride, Fe, Iodine
 |  | 
        |  | 
        
        | Term 
 
        | Serotonin-Selective Treat h/a
 |  | Definition 
 
        | Sumatriptan GI upset, dizzy
 Teach stress/comfort
 |  | 
        |  | 
        
        | Term 
 
        | Anesthetics: General Depress cerebral, spinal cord func
 |  | Definition 
 
        | Propofol Amidate
 ↓HR, ↓ RR, ↓ BP, malignant hyperthermia
 |  | 
        |  | 
        
        | Term 
 
        | Anesthetics: Local Interferes w/ nerve trans of pain
 |  | Definition 
 
        | Lidocaine local irritation of skin
 |  | 
        |  | 
        
        | Term 
 
        | Amphetamines ↑dopamine/NE secretion
 |  | Definition 
 
        | Ritalin Adderall
 hyperact, insomn, restless, talkative
 Adverse: palpitations, tachycardia
 ↓ caffeine
 |  | 
        |  | 
        
        | Term 
 
        | Anorexiants ↑dopamine/NE secretion,suppress appetite
 |  | Definition 
 
        | Meridia hyperact, insomn, restless, talkative
 Adverse: palpitations, tachycardia
 instr re med, diet, & exercise
 |  | 
        |  | 
        
        | Term 
 
        | Analeptics Stimulate CNS control respiration
 |  | Definition 
 
        | Caffeine hyperact, insomn, restless, talkative
 Adverse: palpitations, tachycardia
 DO NOT “OVERUSE”
 |  | 
        |  | 
        
        | Term 
 
        | Parkinson’s Disease Dopaminergic Therapy
 ↑dopamine activity brain
 |  | Definition 
 
        | Carbidopa-levodopa Neuroleptic Malignant Syndrome (hyperthermia, altered LOC, rigidity, profuse sweating); Monitor BP, RR,  (BP↑, RR↓), mental status
 |  | 
        |  | 
        
        | Term 
 
        | Alzheimer’s Disease Cholinesterase Inhibitors
 ↑ACH cerebral cortex (helps to improve memory)
 |  | Definition 
 
        | Aricept confusion, ataxia, depr, hostility, abn tkg; Adverse: sz, hepatotoxicity; Monitor BP,mental status, liver function (AST, ALT, SGOT, AlkPhos)
 |  | 
        |  | 
        
        | Term 
 
        | Anti-Mania Normalizes release of NE, dopamine, ACH
 |  | Definition 
 
        | Lithium = 1.0 to 1.5 mEq/L Toxicity: confusion, lethargy, slurred speech, sz, fine tremor
 |  | 
        |  | 
        
        | Term 
 
        | Antianxiety: Benzodiazepines
 Inhibit GABA, which ↓anxiety lvl
 |  | Definition 
 
        | Diazepam, Lorazepam→ Antagonist: Flumazenil
 ↓RR, ↓HR, ↓BP, drowsy
 |  | 
        |  | 
        
        | Term 
 
        | Sedatives: Barbiturates
 Inhibit GABA, which ↓anxiety lvl
 |  | Definition 
 
        | Secobarbital (Seconal) ↓RR, ↓HR, ↓BP, drowsy
 |  | 
        |  | 
        
        | Term 
 
        | Sedatives:Nondiazepines/Nonbarbiturate Binds to GABA receptors to produce CNS depression
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Antiflatulent Agents Produces thin film that collapses gas bubbles in GI Tract
 |  | Definition 
 
        | Simethicone Shake susp; chew tabs
 |  | 
        |  |