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CMS III - PEDS Test #3 - Study Guide
Winter Semester 2011
27
Medical
Graduate
05/06/2011

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Cards

Term
What is the formula for Mentzer's Index?
Definition
MCV/RBC
Term
What does a Mentzer's Index > 13.5 indicate?
Definition
Iron deficiency
Term
What does a Mentzer's index < 13 indicate?
Definition
Thalassemia
Term
What calculation indicates whether the bone marrow is responding properly to the anemia?
Definition
RPI
Term
What does an RPI > 3 mean?
Definition
increased production indicating hemolysis or blood loss
Term
What does an RPI < 2 mean?
Definition
decreased production or ineffective production for the degree of anemia
Term
What type of anemia is described as Hypochromic/microcytic anemia with a low reticulocyte count and elevated red cell distribution width (RDW)?
Definition
Iron deficiency
Term
In what type of infants is iron deficiency anemia MOST COMMON?
Definition
in bottle-fed infants who receive large amounts of cow’s milk (Ages 9-24mo)
Term
What is the MC type of Anemia in PEDs?
Definition
Iron Deficiency Anemia
Term
With what type of anemia does spooning of the finger nails occur?
Definition
In SEVERE iron deficiency anemia
Term
Pt presents with pallor, irritability, anorexia, tachycardia, cardiac dilation and systolic murmurs, splenomegaly and pica. What condition do you suspect?
Definition
Iron deficiency anemia
Term
What lab value is the 1st to fall in iron deficiency anemia?
Definition
Ferritin Levels
Term
What is the treatment for iron deficiency anemia?
Definition
Supplementation with 3-6 mg/kg of elemental iron in three divided doses for at least 4-6 weeks
Term
Which lab value for iron deficiency anemia is an acute phase reactant?
Definition
Serum Ferritin
Term
When do the total body iron stores begin to decrease in an infant? How is this corrected?
Definition
begin to decline after 6 mo old; add iron to their diets
Term
What lab value is caused by an accumulation when the conversion of protoporphyrin to heme is blocked? What condition is it elevated in?
Definition
Free Erythrocyte Protoporphyrin; Elevated in iron deficiency anemia
Term
After two weeks of treating iron deficiency anemia with iron supplementation, if there is no change in lab values, what should you suspect?
Definition
Blood Loss
Development of Infection
Poor Compliance
Other causes of microcytic anemia
Term
Pt has high TIBC, low serum ferritin, High free erythrocyte protoporphyrin, normal Hgb A or F, High RDW, Anisocytosis and Poikilocytosis. What condition do you suspect?
Definition
Iron-Deficiency Anemia
Term
Pt presents with normal or increased free erythrocyte protoporphyrin, High B-thalessemia and Normal A-thalassemia and a normal RDW with a Mentzer's index < 13. What condition do you suspect ?
Definition
Thalessemia
Term
What factor is deficient in Hemophilia A?
Definition
Factor VIII
Term
Pt presents with delayed blood clotting after trauma, hemarthrosis, retroperitoneal hematomas and CNS bleeds w/out trauma. Labs show a prolonged PT & PTT. What condition do you suspect?
Definition
Hemophilia A - Factor VIII Deficiency
Term
Pt presents with delayed blood clotting after trauma, hemarthrosis, retroperitoneal hematomas and CNS bleeds w/out trauma. Labs show a prolonged PTT. What condition do you suspect?
Definition
Hemophilia B - Factor IX Deficiency
Term
What factor is deficient in Hemophilia B?
Definition
Factor IX (Christmas Factor)
Term
Pt presents with minor bleeding coagulopathies such as spontaneous bleeding and hemarthroses and prolonged PTT?
Definition
Factor XI Disorder
Term
Treatment for Hemophilia A?
Definition
Factor VIII Concentrate
Term
What is the treatment for Hemophilia B?
Definition
Factor IX, FFP or cryoprecipitate
Term
What is the treatment for Factor XI deficiency?
Definition
FFP
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