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CMS II Final FOCUSED Review - ENDOCRINOLOGY
Winter Semester 2011
82
Medical
Graduate
03/25/2011

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Cards

Term
What is the goal BP for diabetes?
Definition
130/80 (135/70)
Term
What lipid value to most closely related to insulin resistance?
Definition
Triglycerides
Term
What should be the goal LDL level for a pt w/DM, and what is the tx for high LDL?
Definition
100; statins
Term
Who is the most important person in long term DM management?
Definition
The patient!
Term
Besides insulin what else is deficient in DM 1?
Definition
Amylin
Term
Which condition is described as Nocturnal hypoglycemia with inc fasting plasma glucose levels in the morning?
Definition
somogyi phenomenon
Term
Which of the following characteristics are true about Byetta?
A - Reduce insulin resistance
B - Enhance insulin secretion
C - Suppress glucagon secretion
D - Slows gastric emptying
Definition
A - Reduce insulin resistance
Term
Pt has newly onset DM2 and has tried exercise and diet however, his HgbA1C is 7.1%, what is the first-line tx?
Definition
metformin
Term
In a pt w/newly onset DM 2, what would you expect to see what?
Definition
high insulin
Term
Which type of diabetes has a large genetic component?
Definition
DM 2
Term
What is the MCC of death in DM 2?
Definition
Cardiovascular dx
Term
Which is the fast acting insulin you can take before meals?
Definition
Lispro (or Aspart, as they are both fast acting)
Term
What med was taken off the market b/c it can give you MI?
Definition
rosiglitazone (Avandia)
Term
What types of meds are sitagliptin (januvia) and saxagliptin (onglyza)?
Definition
DPP4
Term
What happens if you drop glucose too fast in DKA?
Definition
Cerebral edema
Term
Whats the 1st thing you do to treat HNC?
Definition
Large amts of fluids
Term
When do you screen for DM 2?
Definition
begin at 45 y/o and screen q3yrs
Term
At what rate should hyperglycemia associated with DKA be lowered in DKA?
Definition
100/hr
Term
What is the hallmark of DM 2?
Definition
Relative insulin deficiency
Term
Which type of diabetes is characterized by Insulin, islet cells, GAD abs?
Definition
DM 1
Term
How are Incretin mimetics delivered?
Definition
Sub Q
Term
DM1 kid came in hypoglycemia LOC, seizure, what do you give?
Definition
25% dextrose q5-10 mins
Term
What do you give in Gestational DM?
Definition
Insulin
Term
Glucose 875, pH7.34, what is this?
Definition
HCN
Term
ADA cutoff for Hgb A1C?
Definition
6.5%
Term
Most specific test for chronic hyperglycemia and chronic complications?
Definition
Hgb A1C
Term
What are the complications of gestational DM?
Definition
large baby, delivery complications (shoulder distocia), neonate death (NOT maternal risk of DM 1)
Term
Preprandial glucose goal?
Definition
80-150
Term
PE indicator for DM?
Definition
obesity w/central adiposity
Term
Highest risk factor for insulin resistance in DM2?
Definition
Obesity
Term
What is the Pathophys of GDM?
Definition
Insulin antagonist
Term
Best Tx for ESRD?
Definition
Renal transplant
Term
Urine show 150 albumin/day, what is this considered?
Definition
Microalbuminuria
Term
Most related comorbidity to DM?
Definition
HTN
Term
Best tx for HTN in DM?
Definition
ACE I
Term
#1 goal of DM tx?
Definition
glycemic control
Term
What is the best, most controlling insulin dose?
Definition
Continuous infusion
Term
How do you dx DKA?
Definition
Serum ketones
Term
What is the electrolyte imbalance in DKA?
Definition
Hypokalemia
Term
Prophylactic tx for MEN 2?
Definition
Thyroidectomy and lymph node dissection
Term
MC tumor for MEN 2 that is nearly 100%?
Definition
Medullary thyroid CA
Term
What is one of the 1st symptoms seen in MEN 1?
Definition
Cutaneous lesions
Term
Which type of diabetes has peripheral insulin resistance?
Definition
DM 2
Term
Man has fasting glucose of 123 and Hgb A1C of 6.1%, what does he have?
Definition
Prediabetes
Term
If a pt has non-emergent DM what should you try first?
Definition
Lifestyle change
Term
Where are the Parthyroids located?
Definition
embedded posterior to thyroid
Term
Where is the L. adrenal gland located?
Definition
ehind (periotoneal) under spleen
Term
Calculate amt levothyroxine 50kg woman?
Definition
1.7mcg/kg/d = 85
Term
What med is used for nursing mothers who have hyperthyroidism?
Definition
PTU
Term
What meds interact with thyroxine?
Definition
Propranolol
Term
What is the tx for Pheochromocytoma?
Definition
phenoxybenzamine (Dibenzyline) start 10mg BID
Term
What is the tx for DI?
Definition
Desmopressin Acetate/DDAVP (tx) 0.05mg PO BID
Term
What is the tx for dwarfism in children?
Definition
GH 0.025 mg/kg SC daily
Term
In which dz does TSH-R Ab Increase (antibodies to TSH receptors)?
Definition
Grave’s Dz
Term
What is the tx for Acute Adrenocortical Insufficiency?
Definition
Hydrocortisone 100mg IV + saline (5% dextrose)
Term
Which hormone from the anterior pituitary is regulated by an inhibitory hormone?
Definition
PRL
Term
Which condition has abnormal labs of increased ACTH and increased cortisol?
Definition
Cushing’s Dz
Term
What is a 2mm firm nodule on L. Neck most likely?
Definition
Papillary
Term
Which type of tumor secretes GH?
Definition
somatotroph
Term
What condition is described as loss of vision in the temporal fields, caused by a lesion of the optic chiasm?
Definition
Bitemporal Hemianopsia
Term
Which posterior pituitary hormone works on a positive feedback system?
Definition
Oxytocin
Term
Which condition is characterized by an increase in FT4 and low TSH?
Definition
Primary hyperthyroidism
Term
What hormone in the thyroid axis is inhibitory?
Definition
T4
Term
What is the stimulus for Calcitonin secretion?
Definition
hypercalcemia
Term
What are the effects of PTH on the intestines?
Definition
causes them to absorb Ca
Term
Which hormone from the anterior pituitary targets the adrenal gland?
Definition
ACTH
Term
What condition would you suspect if your pt c/o that his hats are no longer fitting?
Definition
Acromegaly
Term
What is a possible cause of galactorrhea in a women once you have r/o pregnancy?
Definition
hyperprolactinemia
Term
If a pt presents within increased ACTH and Increased cortisol levels and a brain MRI is w/in NL, what other test would you complete to r/o another cause of the abnormal levels?
Definition
CT chest r/o small cell carcinoma
Term
What can tagamet (Cimetidine) cause?
Definition
Hyperprolactinemia
Term
What does a + chvostek's sign indicate?
Definition
hypoparathyroidism
Term
What condition must you suspect if an elderly ot shows signs of hyperthyroidism?
Definition
A fib
Term
What cardiovascular symptoms might be a symptom of hyperthyroidism?
Definition
tachycardia
Term
What is the only definitive test for a thyroid nodule?
Definition
FNA
Term
What other cause of hyperthyroid symptoms must you r/o?
Definition
pheochromocytoma
Term
How is pheochromocytoma diagnosed?
Definition
24hr urine – VMA and catecholamines
Term
What test is used to find the levels of PRL?
Definition
PRL fasting AM levels
Term
What is another name for hyperaldosteronism?
Definition
Conn's syndrome
Term
Which condition is described as markedly increased ACTH levels?
Definition
acute adrenocortical insufficiency (Addisonian crisis)
Term
What can a small heart size be indicative of?
Definition
Chronic adreno insufficiency (addison's dz)
Term
What med does insulin interact with?
Definition
levothyroxine
Term
What condition is characterized by decreased ALD and increased renin?
Definition
hypoaldosterone
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