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| synthetic form of a glycoprotein that stimulates RBC production |
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| Used to increase Hbg to 12 prior to surgery or increase time between transfusions |
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Administered in:
CKD
RA
HIV
Chemotherapy |
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| Prescribed under a REMS which includes a medication guide for the patient. |
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| Stimulates bone marrow to produce granulocytes (neutrophils) |
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| Used to treat neutropenia from: chemotherapy, MDS, to increase the # of hematopoeitic cells in blood prior to collection by leukopharesis with stem cell transplant |
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| When is Neupogen contraindicated? |
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| Pts with sensitivity to E Coli derived proteins |
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| What agent is used to treat estrogen or progesterone dependent breast CA? |
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| How long can a pt be treated with Arimidex? |
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| 5 years to limit the risk of endometrial cancer. |
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| What is the main side effect of concern with Arimidex? (aside from endometrial cancer) |
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| decreased bone marrow density which can lead to increased risk of bone fx. |
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| Mitotic inhibitor that induces apoptosis |
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| What medication is given with Taxol to ease side effects? |
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| What types of Cancer is Taxol used to treat? |
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| ovarian, breast, and non-small cell lung cancer. |
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| What is the average rate of resposne to Taxol? |
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| SE: N/V, loss of appetite, thin brittle hair, joint pain, nail color changes, paresthesias in hands,toes |
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| What is the base of cisplatin? |
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| How is Cisplatin administered? |
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| What types of cancer is Cisplatin used to treat? |
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| sarcoma, lymphomas, germ cell tumors, cancer (non-small cell lung, testicular, bladder, cervical, ovarian) |
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| SE: nephrotoxicity, neurotoxicity, ototoxicity, N/V (highly emotogenic), electrolyte disturbances (decreased mag, potassium, and calcium) |
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| Kills bacteria by inducing them to produce molecules toxic to themselves |
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| What medication is used to tx melanoma, refractory CML, metastatic ovarian cancer, squamous cell head & neck cancer. |
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| Adjunct in RX of sickle cell pts with at least 3 painful crises in the past 12 months. |
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| How is hydroxyurea administered? |
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| Why is hair loss a common side effect of chemo? |
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| because hair cells are rapid multipliers and thus some of the first cells targed by chemo. |
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| other common side effects of chemo: |
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| anemia, N/V, diarrhea, decreased infection resistance, increased likelihood of hemorrhaging. |
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