Term
| What are the four main types of tissue found in the body? |
|
Definition
epithelial
connective
neural
muscle |
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Term
| What types of glycerolphospholipids have negative charges at physiological pH? |
|
Definition
| phosphotidylserine, phosphotidylinisotol, cardiolipin |
|
|
Term
|
Definition
| A type of sphingolipid that has a amide linkage and one unsaturated fatty acid chain and one saturated fatty acid chain |
|
|
Term
| Where is cardiolipin exclusively found and in what membrane is it most abundant? |
|
Definition
| inner and outer mitochondrial membrane, more abundant in inner membrane |
|
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Term
| What is the difference between a controlled variable versus a regulated variable? |
|
Definition
| A regulated variable is kept more or less constant while values of the controlled variable to be changed more widely |
|
|
Term
| Name an example of a regulated variable in human physiology |
|
Definition
mean arterial pressure
carbondioxide and oxygen partial pressure
hypothalamic temperature
arterial pH
serum calcium concentration |
|
|
Term
| How does the diffusion rate vary by distance? |
|
Definition
diffusion rate varies by x^2
|
|
|
Term
| What variables determine flux in Fick's Law |
|
Definition
area
permeability
concentration |
|
|
Term
| What are the types of protein mediated transport? What is one example of each? |
|
Definition
passive and active transport
channels
pumps
|
|
|
Term
| What is the main difference between channels and carriers? |
|
Definition
| Channels are usually much faster than carriers in transporting substrates. |
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|
Term
| What are examples of transport carriers located in the basal membrane side of epithelial cells? |
|
Definition
Na/K pump (ATPase)
Na/K/2Cl cotransporter
H+ pump
|
|
|
Term
| What are examples of transport proteins found in the apical membrane of epithelial cells? |
|
Definition
Na/Glucose cotransporter
CFTR (cystic fibrosis transmembrane receptor) |
|
|
Term
| What is the molecular basis of cystic fibrosis? |
|
Definition
CFTR mutation results in impaired function or less of Cl- channel, that result in less secretion of Cl-, Na+, and water. In lungs, where reabsorption of Na+ and water is reduced, this mutation causes secretion from lungs to be dry and thick |
|
|
Term
| What are the clinical features of cystic fibrosis? |
|
Definition
| salty sweat, jaundice, thick mucus in lungs and other bronchopleural issues, mucous plugs in intestines, infertility, pancreatic issues resulting in fat in fecal material |
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Term
| What is the biggest difference between Northern Blot and Souther Blot other than the genetic material used? |
|
Definition
| Since Northern Blot uses RNA, the sample does not need to be digested with endonucleases like Southern Blot, which uses DNA |
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