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CM Neuro Exam 1
neuro exam 1
68
Medical
Graduate
01/17/2012

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Term
hydrocephalus
Definition
impaired circulation or absorption of CSF
Term
symptoms of hydrocephalus
Definition
feeding difficulties, change in academic performance, failure to meet developmental milestones
Term
signs of hydrocephalus
Definition
big head, bulging anterior fontanel, setting sun sign, brisk tendon reflexes, clonus, Macewen Sign
Term
diagnose hydrocephalus
Definition
MRI
Term
treat hydrocephalus
Definition
ventriculoperitoneal shunt, acetozolamide and furosemid (decrease CSF production)
Term
prognosis of hydrocephalus
Definition
untreated can lead to brain herniation
Term
cushings triad
Definition
hypertension, irregular breathing, bradycardia (HIB)
Term
obstructive or non communicating hydrocephalus
Definition
something blocking the ventricles so CSF can't flow out of the ventricular system and into subarachnoid space. most commonly seen in children.
Term
non-obstructive communicating hydrocephalus
Definition
malfunction of arachnoid villi or obliteration of subarachnoid cisterns so CSF can't drain into veinous system. caused by subarachnoid hemorhage, meningitis, or leukemic infiltrates
Term
dandy walker syndrome
Definition
congenital cystic expansion of the fourth ventricle in the posterior fossa from an abnormal development of the cerebellum
Term
arnold chiari malformations
Definition
hind brain problems. localized to chromosomes 9 and 15
Term
arnold chiari type 1
Definition
most common and least severe. mild caudal displacement of the cerebellar tonsils.associated with hydromyelia and syringomyelia.
Term
hydromyelia
Definition
dilation of the central canal of the spinal cord caused by an increase of fluid
Term
syrignomyelia
Definition
fluid filled cabity within teh spinal cord
Term
arnold chiari type 2
Definition
less common and more severe. caudal displacement of the medulla, pons, and 4th ventricle.associated with myelomeningocele.
Term
anencephaly
Definition
defect in calvarium, meninges, and scalp. due to failure of rostral neuropore.
Term
alpha feto protein
Definition
used to detect anencephaly in amniocentesis.
Term
spina bifida occulta
Definition
defect in vertebral arch in L5 to S1 region due to failure of caudal neuropore closure. no clinical symptoms
Term
signs of spina bifida occulta
Definition
tuft of hair above where unfused vertebral arch lies. lipoma, discoloration of skin, tail, dermal sinus in midline of lower back
Term
tethered cord
Definition
progressive deterioration in lower extremity function, changes in urinary tract function, progressive scoliosis, or pain
Term
myelomeningocele
Definition
spinal cord and/or nerve roots in membranous sac protruding through unfused vertebral arch. second most common congenital deformity. genetic factor. ethnic and country of origin play largest role.
Term
CNS dysfunctions with myelomeningocele
Definition
hydrocephalus, chiarai II, syringomyelia. treat with VP shunt.
Term
urologic dysfunctions with myelomeningocele
Definition
neurogenic bladder dysfunction, renal failure. treat with VCUG and RUS after closure, clean intermittent catheterization, anticholinergic and alpha adrenergic stimulators, surgery.
Term
neurogenic bladder dysfunction
Definition
incontinence, UTIs, hydronephrosis
Term
orthopedic dysfunctions in myelomeningocele
Definition
scoliosis, fractures, clubfoot, join contractures, dislocation of hips, kyphosis. treat with casting and surgery
Term
bowel dysmotility
Definition
fecal incontinence with myelomeningocele. manage with timed enemas
Term
cognition/psychosocial dysfunctions with myelomeningocele
Definition
learning problems, seizure disorders, poor in arithmetic, social isolation and depression
Term
latex allergy
Definition
common in kids with myelomeningocele
Term
management of myelomeningocele in neonate
Definition
cover with saline soaked gauze, thorough neuro exam, assess for hydrocephalus, chiari II, orthopedic defects, give antibiotics, surgery to close defect and VP shunt
Term
recommended dose of folic acid for all women of childbearing age
Definition
0.4mg
Term
recomended dose of folic acid for women with risk factors
Definition
4mg
Term
risk factors for neural tube defects
Definition
folic acid deficiency, B12 deficiency, valoproic acid, carbazepine, methotrexate, excessive vitamin A, previous child with neural tube defect, hyperthermia
Term
if screen positive for AFP
Definition
do ultrasound or amniocentesis
Term
predental space
Definition
relationship of dens of C2 to anterior ring of C1. 3mm in adults. 5mm in kids.
Term
jefferson fracture
Definition
C1 vertical compression fracture. due to direct axial loading. lateral masses of C1 displaced laterally, fracture of anterior and posterior rings, disruption of transverse ligament.
Term
extension fracture
Definition
posterior neural arch fracture of C1. lateral masses not displaced.
Term
hangman's fracture
Definition
hyperextension. fracture of posterior neural arch of C2 with spinal cord separation. "traumatic spondylolithesis"
Term
Flexion teardrop fractures
Definition
high impact head on collisions. flexion injury. wedge shaped fragment of the anterior inferior portion of the vertebral body. implies ligamentous disruption with impingement on anterior spinal cord due to fx. hyperkyphosis. vertebra is posteriorly displaced. fragment still attached to anterior longitudinal ligament. quadrapelegia
Term
odontoid fracture
Definition
most common upper cervical fx. if patient awake, complains of high cervical pain with muscle spasm aggravated by movement.
Term
odontoid type I
Definition
avulsion of tip. stable. heals slowly
Term
odontoid type II
Definition
fracture at junction of odontoid and body of C2. most common. heal slowly.
Term
odontoid type III
Definition
fracture through superior aspect of C2. heal more readily.
Term
wedge compression fracture
Definition
diminished height and increased concavity of anterior body of vertebral body. do a CT to look for retropulsion
Term
clay shovelers fracture
Definition
avulsion fractures of the spinous processes of the lower cervical vertebrae
Term
burst fracture
Definition
direct axial load causes burst with fragments going in all directions. unstable. look for retropulsions of fracture into spinal cord
Term
brown sequard
Definition
hemisection of spinal cord. loss of pain and temp on contralateral side. loss of proprioception and fine touch on ipsilateral. loss of motor on ipsilateral.
Term
central cord syndrome
Definition
decussation of fibers in spinothalamic tract conveying pain and temperature compromised initially in a shroud like presentation. vascular in origin. may follow hyperextensio injury in patients with degenerative arthritis. ligamentum flavum buckles into cord resulting in concussion of the central most portion of the cord. neurologic deficits of arms greater than legs.
Term
cauda equina syndrome
Definition
severe injuries below L2, usually ruptured midline intervertebral disc. can also be from tumors. perianal or bilateral leg pain, bowel or bladder dysfunction, saddle anesthesia, deminished rectal sphincter tone, lower extremity weakness. treat with surgery
Term
Neurogenic Shock
Definition
acute spinal cord injury about T6 which causes impairment of the descending sympathetic pathways. hypotension due to loss of vasomotor tone. bradycardia due to unopposed vagal tone to heart. warm well perfused skin. differs from other kinds of shock in that it is bradycardic instead of tachycardic
Term
Anterior Spinal Artery
Definition
supplies anterior 2/3 spinal cord
Term
Posterior Spinal Artery
Definition
supplies posterior 1/3
Term
vascular syndrome of the spinal cord
Definition
occlusion or damage to anterior spinal artery. causes radicular girdle pain. loss of motor function. impaired bowel and bladder control. position sense, vibration, and light touch are intact due to preservation of dorsal column. painful burning below level of injury
Term
lateral corticospinal tract
Definition
voluntary motor function. lesion would lead to upper motor neuron syndrome. somatotopic - legs are lateral
Term
spinothalamic tract
Definition
somatotopic - legs are lateral (opposite of dorsal column). crude touch, pain, temp
Term
fasciculus cuneatus
Definition
fine touch, proprioception arm
Term
fasciculus gracilis
Definition
fine touch, proprioception leg
Term
upper motor neuron lesion
Definition
transection of corticospinal tract or destruction of cortical cells of origin. transverse myelitis.causes spastic paresis, no atrophy, increase DTR, positive Babinski sign
Term
upper motor neuron lesion
Definition
transection of corticospinal tract or destruction of cortical cells of origin. transverse myelitis.causes spastic paresis, no atrophy, increase DTR, positive Babinski sign
Term
lower motor neuron lesion
Definition
damage to motor neurons. poliomyelitis. flaccid paralysis, atrophy, no DTR.
Term
complete transection of cord
Definition
transverse myelopathy. total loss of innervation distal to level of interuption. DTRs may persis. autonomic dysfunction may manifest with hypotension and priapism. if longer than 24 will not have functional recovery.
Term
poliomyelitis
Definition
lower motor neuron. virus destroys motor neurons in anterior horn and brainstem. flaccid paralysis.
Term
amyotrophic lateral sclerosis
Definition
combined UMN and LMN problem. most common neurodegenerative disease. mutation chromosome 21. defective superoxide dismutase 1. muscle weakness. starts in hands. spastisity. babinski sign. NO SENSORY DEFICITS AND NO DEMENTIA. eventual paralysis of respiratory muscles
Term
Tabes dorsalis
Definition
damage to dorsal column. loss of proprioception. Charcots joints. shooting pain. prostitutes pupils. rombergs sign. dementia. syphilis.
Term
syringomyelia
Definition
cavitary lesion within spinal cord. loss of pain and temp in upper extremities with preservation of proprioception and light touch. associated with chiari
Term
vitamin B12 deficiency
Definition
posterolateral column syndrome. loss of proprioception as well as sensory ataxia, rombergs sign. bilateral corticospinal tract dysfunction results in spasticity, hyperreflexia, babinski's sign. treatment of latent TB.
Term
Friedreich's ataxia
Definition
lateral and dorsal column disease. autosomal recessive. deficiency in protein frataxin which is essential for iron metabolism. staggering gait, frequent falling, high arch, hammer toes, hypertrophic cardiomyopathy is cause of death.
Term
artery of adamkeweicz
Definition
large segmental radiculospinal artery located in lumbar region. T9-T12. supplies lower 1/3 cord
Term
Guillian-Barre Syndrome
Definition
lower motor neuron lesion. most common acute peripheral neuropathy. inflammatory demyelinating. after respiratory or GI illness. progressive ascending. loss of DTRs.
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