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Clinical Neuro
Stroke and TIA
28
Biology
Graduate
01/10/2008

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Cards

Term
What's the definition of a TIA?
Definition
Its brief, reversible episodes of focal nonconvulsive ischemic nuerological disturbance lasting secs to hours
Term
A TIA is a warning for what?
Definition
A stroke and Heart attack
Term
A stroke is a disruption of what?
Definition
Blood supply to an area of the brain
Term
A stroke can be _______ or ______ and the later is by far the most common
Definition
hemorrhagic or ischemic
Term
Stroke is the leading cause of what?
Definition
serious, long term disability
Term
TIA can involve any of the cerebral arteries. What are they?
Definition
Carotid, branches of the middle, anterior or posterior cerebral or the vertebro-basilar system
Term
What is a negative symptoms that is often associated w/ TIA
Definition
loss of function, like sensation in the arm is gone
Term
are loss of consciousness, syncope or convulsions associated w/ TIA?
Definition
no
Term
The brain is fed by two pair of arteries, name them
Definition
Carotid and Vertebral
Term
Which veins drain the brain
Definition
Jugular veins
Term
How can you identify the ICA radiographically?
Definition
It doesn't branch until it enters the skull and most of the time there is a bend
Term
Name the advantages and disadvantages in the circle of willis
Definition
An anuerysm and clots can occur anywhere due to the circle. But a clot would not produce a stroke, due to collaterals
Term
What is the first branch of the ICA
Definition
Opthalmic
Term

Name the blood supply areas indicated by the number

[image]

Definition

1. Middle cerebral

2. Posterior cerebral

3. Anterior cerebral

Term
Give the order of events of vascular wall injury
Definition
1. Fibrin traps
2. Platelets
3. Platelet activation
Term
What are the 3 types of ischemic strokes
Definition
1. Emboli
2. Thrombolic: obstructing artery
3. Small vessel disease: Most common
Term
What's the most common ischemic stroke?
Definition
Small vessel disease
Term
What's the clinical presentation of embolic TIA/stroke
Definition
1. Patient is often awake
2. Onset the patient appears stunned
3. Signs and symptoms improve quickly
Term
What' the treatment for embolic TA/strokes?
Definition
Anticoagulation
Term
What's the clinical presentation of thrombotic TIA/strokes
Definition
1. Repeat attacks of similar symptoms
2. Signs and symptoms may progress over time
Term
What's the treatment for thrombotic strokes?
Definition
Identify the arterial lesion and CEA or stent placement
Term
If a person wakes up in the middle of the night to use the bathroom and finds that he has minor weakness on his left side. Goes back to sleep and no longer can move his left side. What happened?
Definition
Thrombotic stroke
Term
What's the clinical presentation of Lacunar TIAs/Strokes
Definition
1. Damage white matter due to micro emboli blocking small vessels
2. Classic symptoms are: Motor, sensory, sensorimotor, clumsy hand dysarthris, ataxia hemiparesis
Term
How do you treat lacunar strokes
Definition
Control HTN, diabetes and smoking
Term
For TIAs short attacks are most likey due to _______ emboli and large attacks are likely due to _____ emboli
Definition
small and large
Term
What are the 4 levels of tissue damage
Definition
1. Core: Irreversibly damaged
2. Ischemic penumbra: Uncertain prognosis
3. Oligaemia Penumbra: At risk only in particular circumstances
4. Not at risk
Term
How long does it take for neurons to exhaust their energy
Definition
2-3 min
Term
Which parts of the brain is most vulnerable to ischemia
Definition
Cerebellum, hippocampus and cortex
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