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Clinical Laboratory Exam 1
Hematology & Iron
10
Other
Graduate
06/30/2010

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Cards

Term
What is the average adult blood volume and what is the composition?
Definition
4-6L
55% plasma, 45% celular elements
Term
Def: Erythorpoises
Definition
maturation in bone marrow through metarubricyte takes 5 days

Reticulocytes mature in 1-2 days in peripheral circulation
Term
What begins the synthesis of hemoglobin?
Definition
Rubricyte
Term
what is metarubicyte?
Definition
maximum hemoglobin synthesis

nucleus ejected
gives cells characteristic boconcave shape when mature
Term
What is the rate at which erythrocytes enter the blood stream?
Definition
2M/sec
Term
What is the rate at which erythrocytes enter the blood stream?
Definition
2M/sec
Term
How long does it take for reticulocytes to mature after it leaves the bone marrow?
Definition
1-2 days
Term
What is produced in the kidneys in response to tissue hypoxia?
Definition
Erythropoietin
Term
What are the steps in negative feedback in response to decreased blood oxygen to the kidneys?
Definition
kidneys increase erythropoietin, bone marrow increases erythrocyte production, erythrocytes increase blood oxygen.
Term
What are the characteristics of the RBC membrane.
Definition
highly elastic

capable of undergoing large membrane extensions without fragmentation

semipermeable lipid bilayer supported by meshlike cytoskeleton
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