| Term 
 
        | What is the average adult blood volume and what is the composition? |  | Definition 
 
        | 4-6L 55% plasma, 45% celular elements
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | maturation in bone marrow through metarubricyte takes 5 days 
 Reticulocytes mature in 1-2 days in peripheral circulation
 |  | 
        |  | 
        
        | Term 
 
        | What begins the synthesis of hemoglobin? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | maximum hemoglobin synthesis 
 nucleus ejected
 gives cells characteristic boconcave shape when mature
 |  | 
        |  | 
        
        | Term 
 
        | What is the rate at which erythrocytes enter the blood stream? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is the rate at which erythrocytes enter the blood stream? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | How long does it take for reticulocytes to mature after it leaves the bone marrow? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is produced in the kidneys in response to tissue hypoxia? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the steps in negative feedback in response to decreased blood oxygen to the kidneys? |  | Definition 
 
        | kidneys increase erythropoietin, bone marrow increases erythrocyte production, erythrocytes increase blood oxygen. |  | 
        |  | 
        
        | Term 
 
        | What are the characteristics of the RBC membrane. |  | Definition 
 
        | highly elastic 
 capable of undergoing large membrane extensions    without fragmentation
 
 semipermeable lipid bilayer supported by meshlike cytoskeleton
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