Term
|
Definition
| plasma, functions in plasma, lipoprotein, pseudocholine, |
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Term
|
Definition
| min concentrations, no known function in plasma, |
|
|
Term
| altered enzyme activity differe effects |
|
Definition
myocardial infaraction
increased cell turn over- hyerparathyroidism
cell proliferation - cancer
enzyme induction - alcohol |
|
|
Term
| three factors effecting diagnosis |
|
Definition
| levels, ratio to isoenzymes, timining |
|
|
Term
| criteria for enzymes in diagonosis |
|
Definition
| cheapy and easy, specific, levels should be proportional to severity of disease, early the better, |
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Term
|
Definition
| distinct forms of the same enzymes, |
|
|
Term
|
Definition
| formed from different genes cytosolic, MDH |
|
|
Term
|
Definition
| made up of different subunits, LDH |
|
|
Term
|
Definition
| same locus has different alleles, different forms in different individuals |
|
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Term
|
Definition
| isoforms, individuals: sialic acid content ALP isoforms. |
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|
Term
|
Definition
|
|
Term
| LDH and myocardial infaraction |
|
Definition
| endothelial cells will rupture, serum levels for LDH 1 and 2 increase, NOrmal is 100-200 |
|
|
Term
| LDH and myocardial infarction in terms of LD1 and LD2 enzymes |
|
Definition
Muscles:LD1,LD2
Blood:LD2, LD1 Shifts in MI |
|
|
Term
| CK Isoenzymes and tissues of origin |
|
Definition
MM(Ck3) Muscle
MB(Ck2) Heart
3-6 hours 15-100 u/l and 10-80
BB(Ck1) Brain |
|
|
Term
| What CK is used to detect MI |
|
Definition
| Heart(mB), because muscle is too large in quantity. |
|
|
Term
|
Definition
| CK is not increased in hemolyrcis or congestive cardiac failrue |
|
|
Term
|
Definition
| muscular dystrophy increases it, total CK is used in this case |
|
|
Term
| Duration of enzymes for Acute MI |
|
Definition
Ck-mb 3-10 12-24 1.5-3
Ck 5-12 18-30
AST 6-12 20-30
LD 8-16 30-48 5-14 |
|
|
Term
| Muscular disorder diagnosis enzymes and purpose |
|
Definition
CK- specific
AST: increase in different types but not specific
Aldolase: converts fructose-1, 6-bisphosphate to DHAP and Glycealdehyde |
|
|
Term
|
Definition
significant increase in MI
Elevated in liver diseases
2 iso-enzymes- cytoplasmic and mitochondrial |
|
|
Term
|
Definition
AST 8-20
ALT- 10-40
increase in liver diseases but ALT more except alcohol |
|
|
Term
| GGT( Gamma Glutamyl transferase |
|
Definition
| GGT elevated in alcohol and jaundice, management of hepatitis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Streptokinase and Urokinase |
|
Definition
|
|
Term
|
Definition
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Term
|
Definition
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