Term
Given the abbreviation give the enzyme:
ACP |
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Definition
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Term
Given the abbreviation give the enzyme:
ALT |
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Definition
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Term
Given the abbreviation give the enzyme:
ALP |
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Definition
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Term
Given the abbreviation give the enzyme:
AMS |
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Definition
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Term
Given the abbreviation give the enzyme:
AST |
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Definition
| Aspartate Aminotransferase |
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Term
Given the abbreviation give the enzyme:
CK |
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Definition
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Term
Given the abbreviation give the enzyme:
GGT |
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Definition
| Gamma-glutamyltransferase |
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Term
Given the abbreviation give the enzyme:
G6PD |
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Definition
| Glucose-6-Phosphate Dehydrogenase |
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Term
Given the abbreviation give the enzyme:
LD |
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Definition
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Term
Given the abbreviation give the enzyme:
LPS |
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Definition
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Term
Given the abbreviation give the enzyme:
SChE |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Pseudocholinesterase |
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Definition
| Organophosphate Poisoning |
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Term
Given the enzyme give the Disease/Organs:
Lipase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Lactate Dehydrogenase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Glucose-6-Phosphate Dehydrogenase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Gamma-glutamyltransferase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Creatine Kinase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Aspartate Aminotransferase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Amylase |
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Definition
Pancreatitis
Pancreas and Salivary Glands |
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Term
Given the enzyme give the Disease/Organs:
Alkaline Phosphatase |
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Definition
| Bone, Liver, and Placenta |
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Term
Given the enzyme give the Disease/Organs:
Alanine Aminotransferase |
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Definition
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Term
Given the enzyme give the Disease/Organs:
Acid Phosphatase |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Liver |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Biliary Obstruction |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Heart Attack |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Skeletal Muscle |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Bone |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Pancreas |
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Definition
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Term
Given the organ what are the enzymes associated with it:
Prostate |
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Definition
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Term
Given the organ what other tests should be performed:
Liver |
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Definition
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Term
Given the organ what other tests should be performed:
Heart Attack |
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Definition
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Term
Given the organ what other tests should be performed:
Bone |
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Definition
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Term
Given the organ what other tests should be performed:
Prostate |
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Definition
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Term
| Highest levels of Lactate Dehydrogenase are seen in what? |
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Definition
| Pernicious anemia and hemolytic anemias, AMI and Hemolysis |
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Term
| Other than Heart, Liver, and Skeletal Muscle what else is Lactate Dehydrogenase associated with? |
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Definition
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Term
| Sources of error with Lactate Dehydrogenase |
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Definition
Avoid any traces of hemolysis
Avoid refrigerating or freezing |
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Term
| At what temperature should you store Lactate Dehydrogenase? |
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Definition
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Term
|
Definition
Highest in Prostate Cancer
Presumptive evidence of semen |
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Term
True or False:
ACP is rarely performed |
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Definition
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Term
| What has ACP been replaced by? |
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Definition
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Term
| What are Bone Illnesses associated with ALP? |
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Definition
Paget's Disease
Osteomalacia and rickets
Bone fractures
Osteoporosis
Childhood/adolescence |
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Term
| What test can you perform for Osteoporosis? |
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Definition
| Ostase - test to monitor response to therapy |
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Term
| What is associated with the Liver and ALP? |
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Definition
| Biliary tract obstruction |
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Term
| To differentiate Bone from Liver in ALP results, what should you do? |
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Definition
| Heat serum to 56 degrees C for 10 minutes |
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Term
| When differentiating Bone from Liver in ALP which serum lives and which dies? |
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Definition
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Term
| Which trimesters are associated with the placenta and ALP? |
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Definition
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Term
| Sources of error with ALP: |
|
Definition
Hemolysis
Run ASAP to prevent serum increases |
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Term
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Definition
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Term
| AST Liver - Up to 100x ULN in |
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Definition
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Term
| AST Liver - Up to 4x ULN in |
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Definition
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Term
| AST Heart - Levels begin to rise within ____ hours of AMI |
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Definition
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Term
| Is AST useful for assessing AMI? |
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Definition
| No, it is too non-specific |
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Term
| AST Skeletal Muscle is often associated with what? |
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Definition
Muscular dystrophy
Crush injuries |
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Term
| Sources of error with AST? |
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Definition
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Term
| Is ALT more specific for the liver than AST? |
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Definition
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Term
| ALT Liver - Levels higher and persist longer than AST in ____ _____ |
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Definition
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Term
True or False:
ALT may increase prior to symptoms of liver cell damage |
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Definition
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Term
Though AST is high in all of the following, which 1 will ALT be high in?
Heart, Liver, or Skeletal Muscle |
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Definition
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Term
|
Definition
| No significant interferences |
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Term
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Definition
Catalyzes breakdown of starches
Normally filtered by glomerulus and detectable in urine |
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Term
| 2 Illnesses associated with Amylase |
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Definition
Acute Pancreatitis
Macroamylasemia |
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Term
| Acute Pancreatitis - AMS levels rise in _______ hours after onset of an attack and return to normal in a _____ |
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Definition
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Term
| ____ levels of AMS in Urine of Acute Pancreatitis patients |
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Definition
|
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Term
| What are the most common causes of Acute Pancreatitis? |
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Definition
|
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Term
| Can Acute Pancreatitis lead to tissue necrosis and death? |
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Definition
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Term
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Definition
Benign condition affecting 1-2% of population.
Amylase binds to immunoglobulins
This bound pair can't filter through glomerulus, thus serum levels rise |
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Term
| Though Serum amylase rises in both Acute Pancreatitis and Macroamylasemia, is Urine Amylase elevated or decreased in Acute Pancreatitis? |
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Definition
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Term
| Though Serum amylase rises in both Acute Pancreatitis and Macroamylasemia, is Urine Amylase elevated or decreased in Macroamylasemia? |
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Definition
|
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Term
|
Definition
| Calcium and Chloride are Activators |
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Term
| Do you use EDTA tubes for Amylase samples? |
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Definition
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Term
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Definition
| Breaks down dietary triglycerides into fatty acids and glycerol |
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Term
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Definition
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Term
| Is LPS elevated in Salivary disorders? |
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Definition
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Term
| Sources of error for Lipase |
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Definition
| Hemolysis inhibits lipase activity to cause a falsely low value |
|
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Term
| Delta-Glutamyltransferase |
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Definition
| Sensitive indicator of alcohol ingestion |
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Term
| What is GGT used to monitor? |
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Definition
| Abstention from alcohol because levels rapidly rise if drinking is resumed |
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Term
| Are there any sources of error for GGT? |
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Definition
| No, it is Relatively Stable |
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Term
| Does Hemolysis interfere with GGT? |
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Definition
|
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Term
| G-6-PD - Most in ___ ___ to maintain NADPH which protects hemoglobin from oxidative damage |
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Definition
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Term
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Definition
|
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Term
| Where is there a high incidence of G6PD? |
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Definition
Africa
Middle East
Far East |
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Term
| G6PD - Exposure to oxidant drugs can cause what? |
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Definition
| Drug-Induced Hemolytic Episode |
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Term
| A Deficiency in G6PD can provide what? |
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Definition
| Some protection against Plasmodium falciparum |
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Term
| Sources of error for G6PD? |
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Definition
|
|
Term
| What is used to test for deficiency of G6PD? |
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Definition
|
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Term
| Pseudocholinesterase & Acetylcholinesterase are needed for what? |
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Definition
| Nerve conduction and muscle contraction/impulse termination |
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Term
| What does an Inherited Deficiency in Pseudocholinesterase & Acetylcholinesterase cause? |
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Definition
| Muscle contraction and respiratory distress when given anesthesia |
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Term
| What does an Acquired Deficiency in Pseudocholinesterase & Acetylcholinesterase cause? |
|
Definition
| Salivation, vomiting, twitching, slurred speech, behavioral changes, and respiratory failure |
|
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Term
| Where does an Acquired Deficiency in Pseudocholinesterase & Acetylcholinesterase come from? |
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Definition
| Organophosphate pesticide poisoning |
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Term
| Creatine Kinase - 3 isoforms are also called |
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Definition
|
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Term
| CK - All three forms contibute to the ____ ___ activity in serum |
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Definition
|
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Term
| CKMM is associated with which organs? |
|
Definition
Skeletal muscle
Heart (95% of total CK) |
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|
Term
| *CKMB is associated with which organs? |
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Definition
|
|
Term
| CKBB is associated with which organs? |
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Definition
|
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Term
| What illnesses are often associated with CKMM? |
|
Definition
| Muscular trauma and crush (rhabdomyolysis), Muscular Dystrophy, Strenuous exercise, AMI |
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Term
| What illnesses are often associated with *CKMB? |
|
Definition
| Acute Myocardial Infarction (AMI) & Angina |
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Term
| What illnesses are often associated with CKBB? |
|
Definition
| Cerebrovascular accidents & Seizures |
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Term
| Name the CK isoenzyme isolated from the heart? |
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Definition
|
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Term
| What test is used to assess treatment of post-menopausal osteoporosis |
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Definition
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Term
| List two "normal" conditions that can cause an elevation of ALP |
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Definition
|
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Term
| Which enzyme(s) require Calcium as an activator? |
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Definition
|
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Term
| List another enzyme other than amylase that can be used to assess pancreatitis |
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Definition
|
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Term
| Which enzyme is Most susceptible to the effects of Hemolysis AND Freezing temperatures |
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Definition
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