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Definition
| Double-walled sac that surrounds heart with a serous membrane between layers |
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Definition
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Definition
| middle layer, cardiac muscle, pumps blood |
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| inner layer; forms valves |
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Definition
| between atria and ventricles |
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Definition
| between ventricles and corresponding arteries |
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Definition
| pacemaker; iniates contractions and located in the right atrium; generates impulses at a basic rate of 70 bpm |
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Definition
| Ventricular depolarization, contraction |
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Definition
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Definition
| ventricular repolarization |
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Definition
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Definition
| contains both actin and myosin |
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Definition
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Term
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Definition
| attachment of actin and associated proteins |
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Term
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Definition
| Large filamentous molecule composed of 6 peptide chains 2 heavy chains and 4 light chains |
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Term
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Definition
| Long filaments polymers of 2 strands of globular monomers |
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Term
| Cardiac Specific troponins |
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Definition
| Troponin T cTnT and Troponin I cTnI |
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Term
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Definition
| Characterized by edema in the lungs, rest of body; caused by coronary artery disease, cardiomyopathies, myocarditis, valvular disease, cardiac arrhythmias |
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Term
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Definition
| an increase in blood urea |
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Term
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Definition
| an increase in N2-containing endproducts including urea, creatinine and uric acid |
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Term
| Brain Natriuretic Peptide (BNP) |
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Definition
| Released in response to ventricle volume expansion and pressure overload, approved for diagnosis of CHF |
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Term
| Chronic Heart Disease Risk Factors |
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Definition
| Hypertension, Sedentary lifestyle, response to stress, diabetes mellitus, hyperlipidemia. |
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Term
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Definition
CHF
Angina pectoris
Myocardial Infarction (MI=heart attack) |
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Term
| Diagnosis of Myocardial Infarction |
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Definition
| Patient history, serum markers, EKG Changes (need 2 out of 3 to make diagnosis) |
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Definition
| Predominantly in brain; closest to the cathode in electrophoresis |
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Term
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Definition
| Relatively specific to heart; in between CK 1-3 for electrophoresis |
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Term
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Definition
| Cardiac and skeletal muscle; stays by the anode in electrophoresis |
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Term
| Myoglobin (Cardiac marker) |
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Definition
Found in skeletal and cardiac muscle.
Rapidly released upon muscle damage
After MI increases 2-4 hours and peaks at 6 hours. |
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Term
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Definition
Hydrophobic, non-polar organic molecules
Diverse structure and function including:
cell membrane components, bile acids, steroid hormones, surfactants, vitamins, energy source |
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Term
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Definition
Caused by increased catabolism of HDL
Defect in catabolism on Apo A-I
Homozygotes may have increased risk of CHD
Heterozygotes exhibit no clinical manifestations |
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Term
Plasma Appearance
Creamy layer on top indicates |
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Definition
| increased chylomicrons (need a fasting sample which this is not) |
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Term
| Plasma appearance is Lipemic (turbid of milky throughout) |
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Definition
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Term
| Plasma appearance is no turbity, slight orange color |
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Definition
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Term
| Plasma appearance is Normal, Clear |
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Definition
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Term
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Definition
| LDL, IDL, Lp(a), Chylomicrons, VLDL, Chylomicron remnants |
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Term
| The majority of the plasma cholesterol is transported by which lipoprotein? |
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Definition
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Term
| High levels of which lipoprotein class are associated with a decrease risk of accelerated atherosclerosis? |
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Definition
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Term
| Important functions of cholesterol |
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Definition
Formation of bile acids
Structural component of cell membranes
precursors of steroid hormones |
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Term
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Definition
| the apoprotein that contributes to the atherogenic properties of LDL particles |
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